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ZFIN ID: ZDB-FIG-100527-11
Chao et al., 2010 - A male with unilateral microphthalmia reveals a role for TMX3 in eye development. PLoS One   5(5):e10565 Full text @ PLoS One
Knockdown Reagent:
Anatomical Terms:
Stage: Day 6

Fig. 9 Morphant larvae show altered formation of the ventral eye.

Fig. 9A–D. Fig. 9A–B. Staining of control injected zebrafish eye with DAPI and FITC at 6 dpf to image zpr-1 shows a strong signal that can be seen at the ciliary margins of the retina. Fig. 9C–D. Staining of anti-ATG morphant (MO1) zebrafish eye with DAPI and FITC at 6 dpf to image zpr-1 shows absent signal for zpr-1 at the ventral region of the retina in an eye with a coloboma, whereas staining at the dorsal region of the retina appears normal. Fish are oriented so that the ventral surface of the eye is seen inferiorly in each photograph.

Gene Expression Details No data available
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
zpr-1 IHC WT control Day 6 ciliary marginal zone
IHC WT + MO1-tmx3a standard conditions Day 6 eye
Phenotype Details No data available
ZFIN wishes to thank the journal PLoS One for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS One