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ZFIN ID: ZDB-FIG-081229-1
Kishi et al., 2008 - The identification of zebrafish mutants showing alterations in senescence-associated biomarkers. PLoS Genetics   4(8):e1000152 Full text @ PLoS Genet.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage Range: Prim-5 to Day 5

Unillustrated author statements

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
atp6v0cahi1207Tg/hi1207Tg standard conditions Long-pec cell aging increased magnitude, abnormal
Long-pec central nervous system necrotic, abnormal
Long-pec pigmentation decreased occurrence, abnormal
Long-pec whole organism low saturation, abnormal
Day 5 eye decreased size, abnormal
Day 5 gut decreased size, abnormal
Day 5 head decreased size, abnormal
Day 5 liver decreased size, abnormal
Day 5 pigmentation decreased occurrence, abnormal
Day 5 whole organism lethal (sensu genetics), abnormal
Day 5 whole organism low saturation, abnormal
atp6v1hhi923Tg/hi923Tg standard conditions Long-pec cell aging increased magnitude, abnormal
Long-pec pigmentation decreased occurrence, abnormal
Long-pec whole organism low saturation, abnormal
Day 5 eye decreased size, abnormal
Day 5 gut decreased size, abnormal
Day 5 head decreased size, abnormal
Day 5 liver decreased size, abnormal
Day 5 pericardium edematous, abnormal
Day 5 pigmentation decreased occurrence, abnormal
Day 5 whole organism low saturation, abnormal
clint1ahi1520Tg/hi1520Tg standard conditions Prim-5 - Long-pec cell aging increased magnitude, abnormal
Prim-5 - Long-pec eye decreased size, abnormal
Prim-5 - Long-pec head decreased size, abnormal
Prim-5 - Long-pec whole organism decreased size, abnormal
Protruding-mouth - Day 5 gut decreased size, abnormal
Protruding-mouth - Day 5 integument texture, abnormal
Protruding-mouth - Day 5 liver decreased size, abnormal
Protruding-mouth - Day 5 pericardium edematous, abnormal
Protruding-mouth - Day 5 whole organism decreased length, abnormal
Protruding-mouth - Day 5 yolk present, abnormal
cnot1hi4201bTg/hi4201bTg standard conditions Protruding-mouth cell aging increased magnitude, abnormal
Protruding-mouth eye decreased size, abnormal
Protruding-mouth head decreased size, abnormal
Day 5 eye decreased size, abnormal
Day 5 gut decreased size, abnormal
Day 5 head decreased size, abnormal
Day 5 head edematous, abnormal
Day 5 liver decreased size, abnormal
Day 5 pericardium edematous, abnormal
dtlhi3627Tg/hi3627Tg standard conditions Long-pec cell aging increased magnitude, abnormal
Long-pec whole organism necrotic, abnormal
Day 5 whole organism lethal (sensu genetics), abnormal
dtlhi447Tg/hi447Tg standard conditions Prim-5 cell aging increased magnitude, abnormal
Prim-5 central nervous system necrotic, abnormal
Prim-5 extension decreased thickness, abnormal
Prim-5 head flat, abnormal
polr2dhi2718bTg/hi2718bTg standard conditions Prim-5 central nervous system necrotic, abnormal
Prim-5 head flat, abnormal
Long-pec cell aging increased magnitude, abnormal
Long-pec whole organism necrotic, abnormal
Day 5 whole organism lethal (sensu genetics), abnormal
polr2glhi3685Tg/hi3685Tg standard conditions Prim-5 cell aging increased magnitude, abnormal
Prim-5 central nervous system necrotic, abnormal
Prim-5 head flat, abnormal
Long-pec cell aging increased magnitude, abnormal
Long-pec extension decreased thickness, abnormal
Long-pec eye decreased size, abnormal
Long-pec head decreased size, abnormal
Long-pec pericardium edematous, abnormal
Long-pec whole organism decreased size, abnormal
Long-pec yolk morphology, abnormal
Day 5 eye decreased size, abnormal
Day 5 head decreased size, abnormal
Day 5 pericardium edematous, abnormal
Day 5 whole organism decreased size, abnormal
Day 5 whole organism lethal (sensu genetics), abnormal
smc1alhi1113aTg/hi1113aTg standard conditions Long-pec cell aging increased magnitude, abnormal
Long-pec central nervous system necrotic, abnormal
Long-pec trunk curved dorsal, abnormal
Long-pec yolk circular, abnormal
Long-pec yolk low brightness, abnormal
Day 5 whole organism lethal (sensu genetics), abnormal
Day 5 whole organism necrotic, abnormal
smc1alhi2068Tg/hi2068Tg standard conditions Protruding-mouth cell aging increased magnitude, abnormal
smc1alhi2327Tg/hi2327Tg standard conditions Protruding-mouth cell aging increased magnitude, abnormal
smc1alhi3821Tg/hi3821Tg standard conditions Protruding-mouth cell aging increased magnitude, abnormal
smohi1640Tg/hi1640Tg standard conditions Long-pec cell aging increased magnitude, abnormal
Long-pec eye decreased distance eye, abnormal
Long-pec eye decreased size, abnormal
Long-pec lateral floor plate aplastic, abnormal
Long-pec pericardium edematous, abnormal
Long-pec secondary motor neuron absent, abnormal
Long-pec somite U-shaped, abnormal
Long-pec trunk curved ventral, abnormal
Long-pec whole organism decreased thickness, abnormal
Long-pec yolk grey, abnormal
Long-pec yolk morphology, abnormal
smohi229Tg/hi229Tg standard conditions Prim-5 cell aging increased magnitude, abnormal
Prim-5 eye decreased distance eye, abnormal
Prim-5 somite U-shaped, abnormal
smohi2329bTg/hi2329bTg standard conditions Day 5 cell aging increased magnitude, abnormal
Day 5 whole organism lethal (sensu genetics), abnormal
spns1hi891Tg/hi891Tg standard conditions Long-pec cell aging increased magnitude, abnormal
Long-pec extension decreased thickness, abnormal
Day 4 whole organism lethal (sensu genetics), abnormal
terfahi1182Tg/hi1182Tg standard conditions Long-pec cell aging increased magnitude, abnormal
Long-pec central nervous system necrotic, abnormal
terfahi3678Tg/+ standard conditions Protruding-mouth retina decreased thickness, abnormal
terfahi3678Tg/hi3678Tg standard conditions Protruding-mouth brain degenerate, abnormal
Protruding-mouth cell aging increased magnitude, abnormal
Protruding-mouth eye decreased size, abnormal
Protruding-mouth head decreased size, abnormal
Protruding-mouth retina degenerate, abnormal
Protruding-mouth spinal cord degenerate, abnormal
Day 5 eye decreased size, abnormal
Day 5 head decreased size, abnormal
Acknowledgments:
ZFIN wishes to thank the journal PLoS Genetics for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS Genet.