ZFIN ID: ZDB-FIG-081013-11
Chiou et al., 2006 - The physiological role of CTGF/CCN2 in zebrafish notochond development and biological analysis of the proximal promoter region. Biochemical and Biophysical Research Communications   349(2):750-758 Full text @ Biochem. Biophys. Res. Commun.
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: 5-9 somites to Day 4

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-ctgfa standard conditions 5-9 somites notochord development disrupted, abnormal
14-19 somites notochord development disrupted, abnormal
Prim-5 notochord development disrupted, abnormal
Prim-25 eye aplastic, abnormal
Prim-25 notochord development disrupted, abnormal
Prim-25 post-vent region shape, abnormal
Long-pec notochord deformed, abnormal
Long-pec notochord development disrupted, abnormal
Long-pec whole organism hypoplastic, abnormal
Pec-fin mandibular arch skeleton decreased size, abnormal
Pec-fin notochord development disrupted, abnormal
Pec-fin somite morphology, abnormal
Pec-fin whole organism hypoplastic, abnormal
Protruding-mouth notochord development disrupted, abnormal
Protruding-mouth whole organism hypoplastic, abnormal
Day 4 notochord development disrupted, abnormal
Day 4 pectoral fin aplastic, abnormal
Day 4 post-vent region decreased length, abnormal
Day 4 post-vent region structure, abnormal
Day 4 telencephalon development disrupted, abnormal
Day 4 whole organism edematous, abnormal
Day 4 whole organism hypoplastic, abnormal
WT + MO2-ctgfa standard conditions 5-9 somites notochord development disrupted, abnormal
Prim-5 notochord development disrupted, abnormal
Prim-25 eye aplastic, abnormal
Prim-25 notochord development disrupted, abnormal
Prim-25 post-vent region shape, abnormal
Long-pec notochord deformed, abnormal
Long-pec notochord development disrupted, abnormal
Long-pec whole organism hypoplastic, abnormal
Pec-fin mandibular arch skeleton decreased size, abnormal
Pec-fin notochord development disrupted, abnormal
Pec-fin somite morphology, abnormal
Pec-fin whole organism hypoplastic, abnormal
Protruding-mouth eye aplastic, abnormal
Protruding-mouth notochord development disrupted, abnormal
Protruding-mouth whole organism hypoplastic, abnormal
Day 4 notochord development disrupted, abnormal
Day 4 pectoral fin aplastic, abnormal
Day 4 post-vent region decreased length, abnormal
Day 4 post-vent region structure, abnormal
Day 4 telencephalon development disrupted, abnormal
Day 4 whole organism edematous, abnormal
Day 4 whole organism hypoplastic, abnormal
Full text @ Biochem. Biophys. Res. Commun.