FIGURE

Fig. 11

ID

ZDB-FIG-080508-34

Publication

Gray et al., 2001 - Zebrafish deadly seven functions in neurogenesis

Other Figures

All Figure Page

Back to All Figure Page

Fig. 11

Notch rescues the des^b420 Mauthner cell defect. Embryos from wild-type or heterozygous desb420 matings were injected at the 1- to 2-cell stage with RNA encoding Notch-ICD-myc (Coffman et al., 1993; Chitnis et al., 1995). Embryos were fixed at 28 h and processed for 3A10 antibody labeling to visualize Mauthner cells. (A) Mock-injected wild-type embryos have one Mauthner cell on either side of hindbrain rhombomere 4. (B) Approximately 25% of mock-injected embryos from a heterozygous des^b420 mating have supernumerary Mauthner cells. Injecting RNA encoding Notch-ICD decreases the number of Mauthner cells in wild-type (C) and des^b420 mutant (D) embryos.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 237(2), Gray, M., Moens, C.B., Amacher, S.L., Eisen, J.S., and Beattie, C.E., Zebrafish deadly seven functions in neurogenesis, 306-323, Copyright (2001) with permission from Elsevier. Full text @ Dev. Biol.