FIGURE

Fig. 2

ID

ZDB-FIG-060627-11

Publication

Chen et al., 2004 - Three modules of zebrafish Mind bomb work cooperatively to promote Delta ubiquitination and endocytosis

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Fig. 2

Hi904 mutation diminishes Notch signaling. (A–E) In situ hybridization with antisense riboprobes of Notch pathway components in embryos at 14 hpf indicates increase of deltaA expression (A), notch1a expression is not significantly different (B), diminished her4 expression (C), and enhanced neurogenin-1 (D) and islet-1 expression (E) in the mutants. (F) Expression of HuC after injection of synthetic RNA encoding the Myc-tagged Notch1a^ICD on one side (marked gray with anti-Myc immunostain) shows blockage of neurogenesis on the injected side in both wild-type and mutant embryos. The inserts are blowups of a part of the images.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 267(2), Chen, W., and Casey Corliss, D., Three modules of zebrafish Mind bomb work cooperatively to promote Delta ubiquitination and endocytosis, 361-373, Copyright (2004) with permission from Elsevier. Full text @ Dev. Biol.