Fig. 1

Oscillating her1 mRNA expression is disrupted in tortuga mutants, but somite boundary formation occurs normally. In situ hybridization in wild type (A, C, E) and tor mutant (B, D, F) embryos indicates that her1 is misexpressed in tor mutant embryos from the beginning of segmentation, and defects get progressively worse as segmentation progresses. Panels are dorsal views, anterior top, with the somite stages indicated in lower left and phenotype indicated in the upper right of each panel. (G, H) Morphological examination shows that tor mutant embryos have segmental pattern, although posterior somites appear more U-shaped in tor mutant embryos compared to the wild type chevron shape. Other defects apparent in this view are head necrosis and reduced posterior yolk. Panels are lateral views of embryos at 24 hpf.