ZFIN ID: ZDB-FIG-051107-5
Honjo et al., 2005 - Slow muscle regulates the pattern of trunk neural crest migration in zebrafish. Development (Cambridge, England)   132(20):4461-4470 Full text @ Development
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Term:
Stage: 20-25 somites

Fig. 5 In segmentation mutants, neural crest migration is disrupted in the same somites in which segmentation is disrupted. Whole-mount staining with a crestin riboprobe of wild-type (A) fss (B), bea (C) and smu mutants (D) at 21 hpf to reveal neural crest cells. (A) In wild-type embryos, neural crest cells migrate in segmental streams along the entire AP axis. (B) Neural crest migration is abnormal from the first somite in fss mutants. (C) In bea mutants, neural crest migration is disrupted posterior to somite 6. (D) In smu mutants there is no clear segmental pattern of neural crest migration; in addition, neural crest cells stall at the level of the dorsal aspect of the notochord. (E,F) EB165 antibody staining reveals that in smu mutants (F) somites are smaller along the DV axis, but a significant amount of fast muscle is still present, although there may be less than in wild types (E). Scale bar: 60 µm in A-D; 25 µm in E,F.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
crestin AB standard conditions 20-25 somites trunk neural crest ISH
dlctm98/tm98 standard conditions 20-25 somites trunk neural crest ISH
smob641/b641(AB) standard conditions 20-25 somites trunk neural crest ISH
tbx6te314a/te314a standard conditions 20-25 somites trunk neural crest ISH
Antibody Labeling Details No data available
Phenotype Details No data available
Acknowledgments:
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development