CRISPR

CRISPR1-fgfr1b

ID
ZDB-CRISPR-200117-3
Name
CRISPR1-fgfr1b
Previous Names
None
Target
Sequence
5' - GGAAGCCAACTAGGACCTGA - 3'
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
uc62 fgfr1b
Expression
Gene expression in Wild Types + CRISPR1-fgfr1b
No data available
Phenotype
Phenotype resulting from CRISPR1-fgfr1b
No data available
Phenotype of all Fish created by or utilizing CRISPR1-fgfr1b
Phenotype Fish Conditions Figures
whole organism fgfr1b expression decreased amount, abnormal fgfr1buc62/uc62 standard conditions Fig. 2 from Leerberg et al., 2019
post-vent region decreased length, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 3 with image from Leerberg et al., 2019
pharyngeal pouch alcama expression decreased amount, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 6 with image from Leerberg et al., 2019
ceratobranchial cartilage absent, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 6 with image from Leerberg et al., 2019
post-vent region decreased length, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 3 with image from Leerberg et al., 2019
pectoral fin bud fgf24 expression decreased amount, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 4 with image from Leerberg et al., 2019
whole organism fgfr1a expression decreased amount, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 2 from Leerberg et al., 2019
Meckel's cartilage shape, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 6 with image from Leerberg et al., 2019
hyosymplectic cartilage absent, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 6 with image from Leerberg et al., 2019
whole organism fgfr1b expression decreased amount, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 2 from Leerberg et al., 2019
apical ectodermal ridge pectoral fin bud dlx2a expression decreased amount, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 4 with image from Leerberg et al., 2019
whole organism fgfr4 expression amount, ameliorated fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 2 from Leerberg et al., 2019
blood accumulation blood island, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 3 with image from Leerberg et al., 2019
somite decreased amount, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 3 with image from Leerberg et al., 2019
blood accumulation blood island, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 3 with image from Leerberg et al., 2019
pharyngeal arch dlx2a expression decreased amount, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 6 with image from Leerberg et al., 2019
post-vent region decreased length, exacerbated fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 3 with image from Leerberg et al., 2019
whole organism fgfr3 expression increased amount, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 2 from Leerberg et al., 2019
presumptive pronephric mesoderm increased distribution, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 3 with image from Leerberg et al., 2019
presumptive pronephric mesoderm increased distribution, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 3 with image from Leerberg et al., 2019
somite morphology, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 3 with image from Leerberg et al., 2019
post-vent region kinked, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 3 with image from Leerberg et al., 2019
post-vent region kinked, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 3 with image from Leerberg et al., 2019
palatoquadrate cartilage shape, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 6 with image from Leerberg et al., 2019
apical ectodermal ridge pectoral fin bud fgf24 expression decreased amount, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 4 with image from Leerberg et al., 2019
apical ectodermal ridge pectoral fin bud fgf8a expression decreased amount, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 4 with image from Leerberg et al., 2019
pectoral fin bud fgf10a expression decreased amount, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 4 with image from Leerberg et al., 2019
notochord posterior region decreased length, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 3 with image from Leerberg et al., 2019
pectoral fin decreased amount, abnormal fgfr1buc62/uc62; fgfr1auc61/uc61 standard conditions Fig. 4 with image from Leerberg et al., 2019
pectoral fin decreased amount, abnormal fgfr1buc62/+; fgfr2uc64/uc64; fgfr1auc61/uc61 standard conditions Fig. 4 with image from Leerberg et al., 2019
presumptive pronephric mesoderm has2 expression increased distribution, abnormal fgfr1buc62/uc62; fgfr2uc64/+; fgfr1auc61/uc61 standard conditions Fig. 7 with image from Leerberg et al., 2019
hyosymplectic cartilage absent, abnormal fgfr1buc62/uc62; fgfr2uc64/+; fgfr1auc61/uc61 standard conditions Fig. 6 with image from Leerberg et al., 2019
Meckel's cartilage shape, abnormal fgfr1buc62/uc62; fgfr2uc64/+; fgfr1auc61/uc61 standard conditions Fig. 6 with image from Leerberg et al., 2019
pectoral fin decreased amount, abnormal fgfr1buc62/uc62; fgfr2uc64/+; fgfr1auc61/uc61 standard conditions Fig. 4 with image from Leerberg et al., 2019
neurocranium incomplete structure, abnormal fgfr1buc62/uc62; fgfr2uc64/+; fgfr1auc61/uc61 standard conditions Fig. 7 with image from Leerberg et al., 2019
trabecula communis split medially, abnormal fgfr1buc62/uc62; fgfr2uc64/+; fgfr1auc61/uc61 standard conditions Fig. 7 with image from Leerberg et al., 2019
palatoquadrate cartilage shape, abnormal fgfr1buc62/uc62; fgfr2uc64/+; fgfr1auc61/uc61 standard conditions Fig. 6 with image from Leerberg et al., 2019
ceratobranchial cartilage absent, abnormal fgfr1buc62/uc62; fgfr2uc64/+; fgfr1auc61/uc61 standard conditions Fig. 6 with image from Leerberg et al., 2019
ceratobranchial cartilage absent, abnormal fgfr1buc62/uc62; fgfr2uc64/uc64; fgfr1auc61/uc61 standard conditions Fig. 6 with image from Leerberg et al., 2019
presumptive pronephric mesoderm has2 expression increased distribution, abnormal fgfr1buc62/uc62; fgfr2uc64/uc64; fgfr1auc61/uc61 standard conditions Fig. 7 with image from Leerberg et al., 2019
ceratohyal cartilage absent, abnormal fgfr1buc62/uc62; fgfr2uc64/uc64; fgfr1auc61/uc61 standard conditions Fig. 6 with image from Leerberg et al., 2019
pectoral fin bud fgf24 expression decreased amount, abnormal fgfr1buc62/uc62; fgfr2uc64/uc64; fgfr1auc61/uc61 standard conditions Fig. 4 with image from Leerberg et al., 2019
whole organism fgfr1a expression decreased amount, abnormal fgfr1buc62/uc62; fgfr2uc64/uc64; fgfr1auc61/uc61 standard conditions Fig. 2 from Leerberg et al., 2019
hyosymplectic cartilage absent, abnormal fgfr1buc62/uc62; fgfr2uc64/uc64; fgfr1auc61/uc61 standard conditions Fig. 6 with image from Leerberg et al., 2019
apical ectodermal ridge pectoral fin bud dlx2a expression decreased amount, abnormal fgfr1buc62/uc62; fgfr2uc64/uc64; fgfr1auc61/uc61 standard conditions Fig. 4 with image from Leerberg et al., 2019
whole organism fgfr1b expression decreased amount, abnormal fgfr1buc62/uc62; fgfr2uc64/uc64; fgfr1auc61/uc61 standard conditions Fig. 2 from Leerberg et al., 2019
whole organism fgfr4 expression amount, ameliorated fgfr1buc62/uc62; fgfr2uc64/uc64; fgfr1auc61/uc61 standard conditions Fig. 2 from Leerberg et al., 2019
pharyngeal arch dlx2a expression decreased amount, abnormal fgfr1buc62/uc62; fgfr2uc64/uc64; fgfr1auc61/uc61 standard conditions Fig. 6 with image from Leerberg et al., 2019
midbrain-hindbrain boundary development disrupted, abnormal fgfr1buc62/uc62; fgfr2uc64/uc64; fgfr1auc61/uc61 standard conditions Fig. 5 with image from Leerberg et al., 2019
pectoral fin field tbx5a expression decreased amount, abnormal fgfr1buc62/uc62; fgfr2uc64/uc64; fgfr1auc61/uc61 standard conditions Fig. 4 with image from Leerberg et al., 2019
whole organism fgfr3 expression increased amount, abnormal fgfr1buc62/uc62; fgfr2uc64/uc64; fgfr1auc61/uc61 standard conditions Fig. 2 from Leerberg et al., 2019
neurocranium incomplete structure, abnormal fgfr1buc62/uc62; fgfr2uc64/uc64; fgfr1auc61/uc61 standard conditions Fig. 7 with image from Leerberg et al., 2019
trabecula communis split medially, abnormal fgfr1buc62/uc62; fgfr2uc64/uc64; fgfr1auc61/uc61 standard conditions Fig. 7 with image from Leerberg et al., 2019
palatoquadrate cartilage shape, abnormal fgfr1buc62/uc62; fgfr2uc64/uc64; fgfr1auc61/uc61 standard conditions Fig. 6 with image from Leerberg et al., 2019
Meckel's cartilage displaced, abnormal fgfr1buc62/uc62; fgfr2uc64/uc64; fgfr1auc61/uc61 standard conditions Fig. 6 with image from Leerberg et al., 2019
apical ectodermal ridge pectoral fin bud fgf24 expression decreased amount, abnormal fgfr1buc62/uc62; fgfr2uc64/uc64; fgfr1auc61/uc61 standard conditions Fig. 4 with image from Leerberg et al., 2019
midbrain hindbrain boundary absent, abnormal fgfr1buc62/uc62; fgfr2uc64/uc64; fgfr1auc61/uc61 standard conditions Fig. 5 with image from Leerberg et al., 2019
apical ectodermal ridge pectoral fin bud fgf8a expression decreased amount, abnormal fgfr1buc62/uc62; fgfr2uc64/uc64; fgfr1auc61/uc61 standard conditions Fig. 4 with image from Leerberg et al., 2019
pectoral fin absent, abnormal fgfr1buc62/uc62; fgfr2uc64/uc64; fgfr1auc61/uc61 standard conditions Fig. 4 with image from Leerberg et al., 2019
pectoral fin bud fgf10a expression decreased amount, abnormal fgfr1buc62/uc62; fgfr2uc64/uc64; fgfr1auc61/uc61 standard conditions Fig. 4 with image from Leerberg et al., 2019
pharyngeal pouch alcama expression decreased amount, abnormal fgfr1buc62/uc62; fgfr2uc64/uc64; fgfr1auc61/uc61 standard conditions Fig. 6 with image from Leerberg et al., 2019
Citations