- Title
-
Nutraceutical Screening in a Zebrafish Model of Muscular Dystrophy: Gingerol as a Possible Food Aid
- Authors
- Licitra, R., Marchese, M., Brogi, L., Fronte, B., Pitto, L., Santorelli, F.M.
- Source
- Full text @ Nutrients
ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions. |
Nutraceutical compounds with positive effects on sapje larvae. The figure illustrates the effects of four nutraceutical molecules on muscle structure (birefringence) and locomotion (distance and velocity) of zebrafish larvae at 4 and 5 dpf, respectively (n = 40 for each experimental group). The error bars show standard error of the mean (SEM). CTRL, untreated sapje; OMO, dystrophic (homozygous) sapje; WT, wild-type-like non-dystrophic (heterozygous) sapje; DEAD, dead fish, ns p > 0.05, * p ≤ 0.05, *** p ≤ 0.001. |
Quantitative real-time PCR analysis of hmox1 mRNA in untreated (wild-type (WT) n = 75; sapje CTRL, n = 75) and in treated (gingerol 4 µM, n = 75) homozygous sapje larvae. The error bars show the standard error of the mean (SEM). * p ≤ 0.05, ns p > 0.05. |