CRISPR

CRISPR1-shank3b

ID

ZDB-CRISPR-180829-1

Name

CRISPR1-shank3b

Previous Names

None

Target

shank3b (1)

Sequence

5' - GGGCGTGTTGTTGCCACGGCCGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
fdu201	shank3b

Expression

Gene expression in Wild Types + CRISPR1-shank3b

No data available

Phenotype

Phenotype resulting from CRISPR1-shank3b

No data available

Phenotype of all Fish created by or utilizing CRISPR1-shank3b

Phenotype	Fish	Conditions	Figures
locomotion decreased occurrence, abnormal	shank3b^{fdu201/fdu201} (TU)	standard conditions	Fig. 3 from Liu et al., 2018
thigmotaxis process quality, abnormal	shank3b^{fdu201/fdu201} (TU)	standard conditions	Fig. 4 from Liu et al., 2018
post-vent region bent, abnormal	shank3b^{fdu201/fdu201} (TU)	standard conditions	Fig. 2 from Liu et al., 2018
embryo development delayed, abnormal	shank3b^{fdu201/fdu201} (TU)	standard conditions	Fig. 2 from Liu et al., 2018
brain Ab3-homer1 labeling decreased amount, abnormal	shank3b^{fdu201/fdu201} (TU)	standard conditions	Fig. 7 from Liu et al., 2018
whole organism decreased life span, abnormal	shank3b^{fdu201/fdu201} (TU)	standard conditions	Fig. 2 from Liu et al., 2018
brain Ab7-syp labeling decreased amount, abnormal	shank3b^{fdu201/fdu201} (TU)	standard conditions	Fig. 7 from Liu et al., 2018
adult locomotory behavior process quality, abnormal	shank3b^{fdu201/fdu201} (TU)	standard conditions	Fig. 4 from Liu et al., 2018
eye Melanin decreased amount, abnormal	shank3b^{fdu201/fdu201} (TU)	standard conditions	Fig. 2 from Liu et al., 2018
brain increased size, abnormal	shank3b^{fdu201/fdu201} (TU)	standard conditions	Fig. 2 from Liu et al., 2018
whole organism decreased velocity, abnormal	shank3b^{fdu201/fdu201} (TU)	standard conditions	Fig. 4 from Liu et al., 2018
social behavior process quality, abnormal	shank3b^{fdu201/fdu201} (TU)	standard conditions	Fig. 5 from Liu et al., 2018
locomotion decreased occurrence, abnormal	shank3b^fdu201/+ (TU)	standard conditions	Fig. 3 from Liu et al., 2018
central nervous system RFP expression decreased amount, abnormal	shank3b^{fdu201/fdu201}; fdu101Tg	standard conditions	Fig. 6 from Liu et al., 2018
neuron development disrupted, abnormal	shank3b^{fdu201/fdu201}; fdu101Tg	standard conditions	Fig. 6 from Liu et al., 2018

Citations