Gene
opn1sw1
- ID
- ZDB-GENE-991109-25
- Name
- opsin 1 (cone pigments), short-wave-sensitive 1
- Symbol
- opn1sw1 Nomenclature History
- Previous Names
-
- SWS1 (1)
- uvops
- zfuv
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have G protein-coupled photoreceptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; cellular response to light stimulus; and phototransduction. Predicted to localize to integral component of plasma membrane and photoreceptor outer segment. Human ortholog(s) of this gene implicated in blue color blindness. Is expressed in several structures, including digestive system; endocrine system; heart; photoreceptor cell; and visual system. Orthologous to human OPN1SW (opsin 1, short wave sensitive).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 87 figures from 61 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73050 (2 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Yoshimatsu et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| blue color blindness | Alliance | Colorblindness, tritan | 190900 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR027430 | Visual pigments (opsins) retinal binding site |
| Domain | IPR017452 | GPCR, rhodopsin-like, 7TM |
| Family | IPR000276 | G protein-coupled receptor, rhodopsin-like |
| Family | IPR001521 | Opsin, blue sensitive |
| Family | IPR001760 | Opsin |
| Family | IPR050125 | G-protein coupled receptor opsins |
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G-protein coupled receptor opsins | G protein-coupled receptor, rhodopsin-like | Opsin | Opsin, blue sensitive | Visual pigments (opsins) retinal binding site |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q9W6A9
|
336 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
opn1sw1-201
(1)
|
Ensembl | 1,777 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab2-opn1sw1 |
|
ABclonal
|
1 | ||||
| Ab1-opn1sw1 | polyclonal | Rabbit |
|
43 |
Plasmids
No data available