Gene
pcf11
- ID
- ZDB-GENE-041114-175
- Name
- PCF11 cleavage and polyadenylation factor subunit
- Symbol
- pcf11 Nomenclature History
- Previous Names
-
- im:6912257
- im:7138745 (1)
- wu:fc47a05
- zgc:175013
- zgc:92226
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable RNA polymerase II complex binding activity and mRNA binding activity. Acts upstream of or within regulation of termination of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of mRNA cleavage factor complex. Predicted to be active in cytoplasm. Orthologous to human PCF11 (PCF11 cleavage and polyadenylation factor subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Kamieniarz-Gdula et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002014 | VHS domain |
| Domain | IPR006569 | CID domain |
| Domain | IPR021605 | Pcf11, Clp1-ID |
| Domain | IPR047415 | Pcf11, CID domain |
| Domain | IPR048830 | Pre-mRNA cleavage complex 2 protein Pcf11, helical domain |
| Domain | IPR048832 | PCF11, charged region |
| Domain | IPR054127 | Pcf11, C-terminal domain |
| Family | IPR045154 | Protein PCF11-like |
| Homologous_superfamily | IPR008942 | ENTH/VHS |
Domain Details Per Protein
| Protein | Additional Resources | Length | CID domain | ENTH/VHS | PCF11, charged region | Pcf11, CID domain | Pcf11, Clp1-ID | Pcf11, C-terminal domain | Pre-mRNA cleavage complex 2 protein Pcf11, helical domain | Protein PCF11-like | VHS domain |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q5U393 | InterPro | 1457 |
Interactions and Pathways
No data available
Plasmids
No data available