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ZFIN ID:
ZDB-MIRNAG-090112-2
CITATIONS
(41 total)
miRNA Gene Name:
microRNA 126a
miRNA Gene Symbol:
mir126a
Banjo, T., Grajcarek, J., Yoshino, D., Osada, H., Miyasaka, K.Y., Kida, Y.S., Ueki, Y., Nagayama, K., Kawakami, K., Matsumoto, T., Sato, M., and Ogura, T. (2013) Haemodynamically dependent valvulogenesis of zebrafish heart is mediated by flow-dependent expression of miR-21. Nature communications. 4:1978
Chen, J., Zhu, R.F., Li, F.F., Liang, Y.L., Wang, C., Qin, Y.W., Huang, S., Zhao, X.X., Jing, Q. (2016) MicroRNA-126a Directs Lymphangiogenesis Through Interacting With Chemokine and Flt4 Signaling in Zebrafish. Arteriosclerosis, Thrombosis, and Vascular Biology. 36(12):2381-2393
Craig, T.A., Zhang, Y., Magis, A.T., Funk, C.C., Price, N.D., Ekker, S.C., Kumar, R. (2014) Detection of 1,25-Dihydroxyvitamin D-Regulated miRNAs in Zebrafish by Whole Transcriptome Sequencing. Zebrafish. 11(3):207-18
Desvignes, T., Bardou, P., Montfort, J., Sydes, J., Guyomar, C., George, S., Postlethwait, J.H., Bobe, J. (2022) FishmiRNA: An evolutionarily supported microRNA annotation and expression database for ray-finned fishes. Molecular Biology and Evolution. 39(2)
Domingues, W.B., Silveira, T.L.R., Nunes, L.S., Blodorn, E.B., Schneider, A., Corcine, C.D., Varela Junior, A.S., Acosta, I.B., Kütter, M.T., Greif, G., Robello, C., Pinhal, D., Marins, L.F., Campos, V.F. (2021) GH Overexpression Alters Spermatic Cells MicroRNAome Profile in Transgenic Zebrafish. Frontiers in genetics. 12:704778
Fish, J.E., Santoro, M.M., Morton, S.U., Yu, S., Yeh, R.F., Wythe, J.D., Ivey, K.N., Bruneau, B.G., Stainier, D.Y., and Srivastava, D. (2008) miR-126 regulates angiogenic signaling and vascular integrity. Developmental Cell. 15(2):272-284
Francia, S., Michelini, F., Saxena, A., Tang, D., de Hoon, M., Anelli, V., Mione, M., Carninci, P., and di Fagagna, F.D. (2012) Site-specific DICER and DROSHA RNA products control the DNA-damage response. Nature. 488(7410):231-235
Grabher, C., Payne, E.M., Johnston, A.B., Bolli, N., Lechman, E., Dick, J.E., Kanki, J.P., and Look, A.T. (2011) Zebrafish microRNA-126 determines hematopoietic cell fate through c-Myb. Leukemia. 25(3):506-514
He, X., Yan, Y.L., Delaurier, A., and Postlethwait, J.H. (2011) Observation of miRNA Gene Expression in Zebrafish Embryos by In Situ Hybridization to MicroRNA Primary Transcripts. Zebrafish. 8(1):1-8
Her, G.M., Hsu, C.C., Hong, J.R., Lai, C.Y., Hsu, M.C., Pang, H.W., Chan, S.K., and Pai, W.Y. (2011) Overexpression of gankyrin induces liver steatosis in zebrafish (Danio rerio). Biochimica et biophysica acta. Molecular and cell biology of lipids. 1811(9):536-48
Kasper, D.M., Moro, A., Ristori, E., Narayanan, A., Hill-Teran, G., Fleming, E., Moreno-Mateos, M., Vejnar, C.E., Zhang, J., Lee, D., Gu, M., Gerstein, M., Giraldez, A., Nicoli, S. (2017) MicroRNAs Establish Uniform Traits during the Architecture of Vertebrate Embryos. Developmental Cell. 40:552-565.e5
King, B.L., Yin, V.P. (2016) A Conserved MicroRNA Regulatory Circuit Is Differentially Controlled during Limb/Appendage Regeneration. PLoS One. 11:e0157106
Kontarakis, Z., Rossi, A., Ramas, S., Dellinger, M.T., Stainier, D.Y.R. (2018) Mir-126 is a conserved modulator of lymphatic development. Developmental Biology. 437(2):120-130
Lagendijk, A.K., Goumans, M.J., Burkhard, S.B., and Bakkers, J. (2011) MicroRNA-23 Restricts Cardiac Valve Formation by Inhibiting Has2 and Extracellular Hyaluronic Acid Production. Circulation research. 109(6):649-57
Lv, H., Liu, B., Qin, Y. (2020) Isosorbide mononitrate promotes angiogenesis in embryonic development of zebrafish. Genetics and Molecular Biology. 43:20190233
Moro, A., Driscoll, T.P., Boraas, L.C., Armero, W., Kasper, D.M., Baeyens, N., Jouy, C., Mallikarjun, V., Swift, J., Ahn, S.J., Lee, D., Zhang, J., Gu, M., Gerstein, M., Schwartz, M., Nicoli, S. (2019) MicroRNA-dependent regulation of biomechanical genes establishes tissue stiffness homeostasis. Nature cell biology. 21(3):348-358
Nepal, C., Coolen, M., Hadzhiev, Y., Cussigh, D., Mydel, P., Steen, V.M., Carninci, P., Andersen, J.B., Bally-Cuif, L., Müller, F., Lenhard, B. (2016) Transcriptional, post-transcriptional and chromatin-associated regulation of pri-miRNAs, pre-miRNAs and moRNAs. Nucleic acids research. 44(7):3070-81
Nicoli, S., Standley, C., Walker, P., Hurlstone, A., Fogarty, K.E., and Lawson, N.D. (2010) MicroRNA-mediated integration of haemodynamics and Vegf signalling during angiogenesis. Nature. 464(7292):1196-1200
Novodvorsky, P., Watson, O., Gray, C., Wilkinson, R.N., Reeve, S., Smythe, C., Beniston, R., Plant, K., Maguire, R., M K Rothman, A., Elworthy, S., van Eeden, F.J., Chico, T.J. (2015) klf2ash317 Mutant Zebrafish Do Not Recapitulate Morpholino-Induced Vascular and Haematopoietic Phenotypes. PLoS One. 10:e0141611
Pauli, A., Montague, T.G., Lennox, K.A., Behlke, M.A., Schier, A.F. (2015) Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish. PLoS One. 10:e0139504
Presslauer, C., Tilahun Bizuayehu, T., Kopp, M., Fernandes, J.M., Babiak, I. (2017) Dynamics of miRNA transcriptome during gonadal development of zebrafish. Scientific Reports. 7:43850
Renz, M., Otten, C., Faurobert, E., Rudolph, F., Zhu, Y., Boulday, G., Duchene, J., Mickoleit, M., Dietrich, A.C., Ramspacher, C., Steed, E., Manet-Dupé, S., Benz, A., Hassel, D., Vermot, J., Huisken, J., Tournier-Lasserve, E., Felbor, U., Sure, U., Albiges-Rizo, C., Abdelilah-Seyfried, S. (2015) Regulation of β1 Integrin-Klf2-Mediated Angiogenesis by CCM Proteins. Developmental Cell. 32:181-190
Sessa, R., Seano, G., di Blasio, L., Gagliardi, P.A., Isella, C., Medico, E., Cotelli, F., Bussolino, F., and Primo, L. (2012) The miR-126 regulates Angiopoietin-1 signaling and vessel maturation by targeting p85beta. Biochimica et biophysica acta. Molecular cell research. 1823(10):1925-1935
Siegerist, F., Lange, T., Iervolino, A., Koppe, T.M., Zhou, W., Capasso, G., Endlich, K., Endlich, N. (2021) Evaluation of endogenous miRNA reference genes across different zebrafish strains, developmental stages and kidney disease models. Scientific Reports. 11:22894
Wienholds, E., Kloosterman, W.P., Miska, E., Alvarez-Saavedra, E., Berezikov, E., de Bruijn, E., Horvitz, R.H., Kauppinen, S., and Plasterk, R.H. (2005) MicroRNA Expression in Zebrafish Embryonic Development. Science (New York, N.Y.). 309(5732):310-311
Wright, K., Han, D.J., Song, R., de Silva, K., Plain, K.M., Purdie, A.C., Shepherd, A., Chin, M., Hortle, E., Wong, J.J., Britton, W.J., Oehlers, S.H. (2024) Zebrafish
tsc1
and
cxcl12a
increase susceptibility to mycobacterial infection. Life science alliance. 7(4):
Xiao, A., Wang, Z., Hu, Y., Wu, Y., Luo, Z., Yang, Z., Zu, Y., Li, W., Huang, P., Tong, X., Zhu, Z., Lin, S., and Zhang, B. (2013) Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish. Nucleic acids research. 41(14):e141
Yi, T., Arthanari, H., Akabayov, B., Song, H., Papadopoulos, E., Qi, H.H., Jedrychowski, M., Güttler, T., Guo, C., Luna, R.E., Gygi, S.P., Huang, S.A., Wagner, G. (2015) eIF1A augments Ago2-mediated Dicer-independent miRNA biogenesis and RNA interference. Nature communications. 6:7194
Zapilko, V., Fish, R.J., Garcia, A., Reny, J.L., Dunoyer-Geindre, S., Lecompte, T., Neerman-Arbez, M., Fontana, P. (2020) MicroRNA-126 is a regulator of platelet-supported thrombin generation. Platelets. 31(6):746-755
Zhang, X., Li, Y., Zhang, Y., Li, S. (2021) Characterization of small RNAs in early zebrafish PGCs. Acta biochimica et biophysica Sinica. 53(4):514-516
Zhang, X., Yang, F., Liu, F., Tian, Q., Hu, M., Li, P., Zeng, Y. (2022) Conservation of Differential Animal MicroRNA Processing by Drosha and Dicer. Frontiers in molecular biosciences. 8:730006
Zhao, Y., Xiong, Q., and Xie, P. (2011) Analysis of MicroRNA Expression in Embryonic Developmental Toxicity Induced by MC-RR. PLoS One. 6(7):e22676
Zou, J., Li, W.Q., Li, Q., Li, X.Q., Zhang, J.T., Liu, G.Q., Chen, J., Qiu, X.X., Tian, F.J., Wang, Z.Z., Zhu, N., Qin, Y.W., Shen, B., Liu, T.X., and Jing, Q. (2011) Two Functional MicroRNA-126s Repress a Novel Target Gene p21-Activated Kinase 1 to Regulate Vascular Integrity in Zebrafish. Circulation research. 108(2):201-209
Wright, K., Han, D.J., Song, R., de Silva, K., Plain, K.M., Purdie, A.C., Shepherd, A., Chin, M., Hortle, E., Wong, J.J., Britton, W.J., Oehlers, S.H. (2024) Zebrafish
tsc1
and
cxcl12a
increase susceptibility to mycobacterial infection. Life science alliance. 7(4):
Desvignes, T., Bardou, P., Montfort, J., Sydes, J., Guyomar, C., George, S., Postlethwait, J.H., Bobe, J. (2022) FishmiRNA: An evolutionarily supported microRNA annotation and expression database for ray-finned fishes. Molecular Biology and Evolution. 39(2)
Zhang, X., Yang, F., Liu, F., Tian, Q., Hu, M., Li, P., Zeng, Y. (2022) Conservation of Differential Animal MicroRNA Processing by Drosha and Dicer. Frontiers in molecular biosciences. 8:730006
Domingues, W.B., Silveira, T.L.R., Nunes, L.S., Blodorn, E.B., Schneider, A., Corcine, C.D., Varela Junior, A.S., Acosta, I.B., Kütter, M.T., Greif, G., Robello, C., Pinhal, D., Marins, L.F., Campos, V.F. (2021) GH Overexpression Alters Spermatic Cells MicroRNAome Profile in Transgenic Zebrafish. Frontiers in genetics. 12:704778
Siegerist, F., Lange, T., Iervolino, A., Koppe, T.M., Zhou, W., Capasso, G., Endlich, K., Endlich, N. (2021) Evaluation of endogenous miRNA reference genes across different zebrafish strains, developmental stages and kidney disease models. Scientific Reports. 11:22894
Zhang, X., Li, Y., Zhang, Y., Li, S. (2021) Characterization of small RNAs in early zebrafish PGCs. Acta biochimica et biophysica Sinica. 53(4):514-516
Lv, H., Liu, B., Qin, Y. (2020) Isosorbide mononitrate promotes angiogenesis in embryonic development of zebrafish. Genetics and Molecular Biology. 43:20190233
Zapilko, V., Fish, R.J., Garcia, A., Reny, J.L., Dunoyer-Geindre, S., Lecompte, T., Neerman-Arbez, M., Fontana, P. (2020) MicroRNA-126 is a regulator of platelet-supported thrombin generation. Platelets. 31(6):746-755
Moro, A., Driscoll, T.P., Boraas, L.C., Armero, W., Kasper, D.M., Baeyens, N., Jouy, C., Mallikarjun, V., Swift, J., Ahn, S.J., Lee, D., Zhang, J., Gu, M., Gerstein, M., Schwartz, M., Nicoli, S. (2019) MicroRNA-dependent regulation of biomechanical genes establishes tissue stiffness homeostasis. Nature cell biology. 21(3):348-358
Kontarakis, Z., Rossi, A., Ramas, S., Dellinger, M.T., Stainier, D.Y.R. (2018) Mir-126 is a conserved modulator of lymphatic development. Developmental Biology. 437(2):120-130
Kasper, D.M., Moro, A., Ristori, E., Narayanan, A., Hill-Teran, G., Fleming, E., Moreno-Mateos, M., Vejnar, C.E., Zhang, J., Lee, D., Gu, M., Gerstein, M., Giraldez, A., Nicoli, S. (2017) MicroRNAs Establish Uniform Traits during the Architecture of Vertebrate Embryos. Developmental Cell. 40:552-565.e5
Presslauer, C., Tilahun Bizuayehu, T., Kopp, M., Fernandes, J.M., Babiak, I. (2017) Dynamics of miRNA transcriptome during gonadal development of zebrafish. Scientific Reports. 7:43850
Chen, J., Zhu, R.F., Li, F.F., Liang, Y.L., Wang, C., Qin, Y.W., Huang, S., Zhao, X.X., Jing, Q. (2016) MicroRNA-126a Directs Lymphangiogenesis Through Interacting With Chemokine and Flt4 Signaling in Zebrafish. Arteriosclerosis, Thrombosis, and Vascular Biology. 36(12):2381-2393
King, B.L., Yin, V.P. (2016) A Conserved MicroRNA Regulatory Circuit Is Differentially Controlled during Limb/Appendage Regeneration. PLoS One. 11:e0157106
Nepal, C., Coolen, M., Hadzhiev, Y., Cussigh, D., Mydel, P., Steen, V.M., Carninci, P., Andersen, J.B., Bally-Cuif, L., Müller, F., Lenhard, B. (2016) Transcriptional, post-transcriptional and chromatin-associated regulation of pri-miRNAs, pre-miRNAs and moRNAs. Nucleic acids research. 44(7):3070-81
Novodvorsky, P., Watson, O., Gray, C., Wilkinson, R.N., Reeve, S., Smythe, C., Beniston, R., Plant, K., Maguire, R., M K Rothman, A., Elworthy, S., van Eeden, F.J., Chico, T.J. (2015) klf2ash317 Mutant Zebrafish Do Not Recapitulate Morpholino-Induced Vascular and Haematopoietic Phenotypes. PLoS One. 10:e0141611
Pauli, A., Montague, T.G., Lennox, K.A., Behlke, M.A., Schier, A.F. (2015) Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish. PLoS One. 10:e0139504
Renz, M., Otten, C., Faurobert, E., Rudolph, F., Zhu, Y., Boulday, G., Duchene, J., Mickoleit, M., Dietrich, A.C., Ramspacher, C., Steed, E., Manet-Dupé, S., Benz, A., Hassel, D., Vermot, J., Huisken, J., Tournier-Lasserve, E., Felbor, U., Sure, U., Albiges-Rizo, C., Abdelilah-Seyfried, S. (2015) Regulation of β1 Integrin-Klf2-Mediated Angiogenesis by CCM Proteins. Developmental Cell. 32:181-190
Yi, T., Arthanari, H., Akabayov, B., Song, H., Papadopoulos, E., Qi, H.H., Jedrychowski, M., Güttler, T., Guo, C., Luna, R.E., Gygi, S.P., Huang, S.A., Wagner, G. (2015) eIF1A augments Ago2-mediated Dicer-independent miRNA biogenesis and RNA interference. Nature communications. 6:7194
Craig, T.A., Zhang, Y., Magis, A.T., Funk, C.C., Price, N.D., Ekker, S.C., Kumar, R. (2014) Detection of 1,25-Dihydroxyvitamin D-Regulated miRNAs in Zebrafish by Whole Transcriptome Sequencing. Zebrafish. 11(3):207-18
Banjo, T., Grajcarek, J., Yoshino, D., Osada, H., Miyasaka, K.Y., Kida, Y.S., Ueki, Y., Nagayama, K., Kawakami, K., Matsumoto, T., Sato, M., and Ogura, T. (2013) Haemodynamically dependent valvulogenesis of zebrafish heart is mediated by flow-dependent expression of miR-21. Nature communications. 4:1978
Xiao, A., Wang, Z., Hu, Y., Wu, Y., Luo, Z., Yang, Z., Zu, Y., Li, W., Huang, P., Tong, X., Zhu, Z., Lin, S., and Zhang, B. (2013) Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish. Nucleic acids research. 41(14):e141
Francia, S., Michelini, F., Saxena, A., Tang, D., de Hoon, M., Anelli, V., Mione, M., Carninci, P., and di Fagagna, F.D. (2012) Site-specific DICER and DROSHA RNA products control the DNA-damage response. Nature. 488(7410):231-235
Sessa, R., Seano, G., di Blasio, L., Gagliardi, P.A., Isella, C., Medico, E., Cotelli, F., Bussolino, F., and Primo, L. (2012) The miR-126 regulates Angiopoietin-1 signaling and vessel maturation by targeting p85beta. Biochimica et biophysica acta. Molecular cell research. 1823(10):1925-1935
Grabher, C., Payne, E.M., Johnston, A.B., Bolli, N., Lechman, E., Dick, J.E., Kanki, J.P., and Look, A.T. (2011) Zebrafish microRNA-126 determines hematopoietic cell fate through c-Myb. Leukemia. 25(3):506-514
He, X., Yan, Y.L., Delaurier, A., and Postlethwait, J.H. (2011) Observation of miRNA Gene Expression in Zebrafish Embryos by In Situ Hybridization to MicroRNA Primary Transcripts. Zebrafish. 8(1):1-8
Her, G.M., Hsu, C.C., Hong, J.R., Lai, C.Y., Hsu, M.C., Pang, H.W., Chan, S.K., and Pai, W.Y. (2011) Overexpression of gankyrin induces liver steatosis in zebrafish (Danio rerio). Biochimica et biophysica acta. Molecular and cell biology of lipids. 1811(9):536-48
Lagendijk, A.K., Goumans, M.J., Burkhard, S.B., and Bakkers, J. (2011) MicroRNA-23 Restricts Cardiac Valve Formation by Inhibiting Has2 and Extracellular Hyaluronic Acid Production. Circulation research. 109(6):649-57
Zhao, Y., Xiong, Q., and Xie, P. (2011) Analysis of MicroRNA Expression in Embryonic Developmental Toxicity Induced by MC-RR. PLoS One. 6(7):e22676
Zou, J., Li, W.Q., Li, Q., Li, X.Q., Zhang, J.T., Liu, G.Q., Chen, J., Qiu, X.X., Tian, F.J., Wang, Z.Z., Zhu, N., Qin, Y.W., Shen, B., Liu, T.X., and Jing, Q. (2011) Two Functional MicroRNA-126s Repress a Novel Target Gene p21-Activated Kinase 1 to Regulate Vascular Integrity in Zebrafish. Circulation research. 108(2):201-209
Nicoli, S., Standley, C., Walker, P., Hurlstone, A., Fogarty, K.E., and Lawson, N.D. (2010) MicroRNA-mediated integration of haemodynamics and Vegf signalling during angiogenesis. Nature. 464(7292):1196-1200
Fish, J.E., Santoro, M.M., Morton, S.U., Yu, S., Yeh, R.F., Wythe, J.D., Ivey, K.N., Bruneau, B.G., Stainier, D.Y., and Srivastava, D. (2008) miR-126 regulates angiogenic signaling and vascular integrity. Developmental Cell. 15(2):272-284
Wienholds, E., Kloosterman, W.P., Miska, E., Alvarez-Saavedra, E., Berezikov, E., de Bruijn, E., Horvitz, R.H., Kauppinen, S., and Plasterk, R.H. (2005) MicroRNA Expression in Zebrafish Embryonic Development. Science (New York, N.Y.). 309(5732):310-311
Additional Citations (8):
Zebrafish Nomenclature Committee (2018) Nomenclature Data Curation (2018). Nomenclature Committee Submission.
Zebrafish Nomenclature Committee (2003) Nomenclature Data Curation (2003-2010). Nomenclature Committee Submission.
ZFIN Staff (2019) Semi-automated association of ENSDARG and ENSDART identifiers with ZFIN genes and transcripts. Semi-automated Curation.
ZFIN Staff (2023) Curation of NCBI Gene Data Via Shared Ensembl IDs (Supplemental NCBI Load). Automated Data Submission.
ZFIN Staff (2002) Scientific Curation. Manually curated data.
ZFIN Staff (2003) Curation of orthology data. Manually curated data.
ZFIN Staff (2008) Curation of miRBase Links. Automated Data Submission.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
ZFIN Staff (2023) Curation of NCBI Gene Data Via Shared Ensembl IDs (Supplemental NCBI Load). Automated Data Submission.
ZFIN Staff (2019) Semi-automated association of ENSDARG and ENSDART identifiers with ZFIN genes and transcripts. Semi-automated Curation.
Zebrafish Nomenclature Committee (2018) Nomenclature Data Curation (2018). Nomenclature Committee Submission.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
ZFIN Staff (2008) Curation of miRBase Links. Automated Data Submission.
Zebrafish Nomenclature Committee (2003) Nomenclature Data Curation (2003-2010). Nomenclature Committee Submission.
ZFIN Staff (2003) Curation of orthology data. Manually curated data.
ZFIN Staff (2002) Scientific Curation. Manually curated data.
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