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ZFIN ID:
ZDB-GENE-060623-2
CITATIONS
(35 total)
Gene Name:
fibroblast growth factor 21
Gene Symbol:
fgf21
Beler, M., Cansız, D., Ünal, İ., Üstündağ, Ü.V., Dandin, E., Ak, E., Alturfan, A.A., Emekli-Alturfan, E. (2022) Bisphenol A reveals its obesogenic effects through disrupting glucose tolerance, oxidant-antioxidant balance, and modulating inflammatory cytokines and fibroblast growth factor in zebrafish. Toxicology and industrial health. 38:19-28
Blanco, A.M., Bertucci, J.I., Unniappan, S. (2020) FGF21 Mimics a Fasting-Induced Metabolic State and Increases Appetite in Zebrafish. Scientific Reports. 10:6993
Brun, N.R., van Hage, P., Hunting, E.R., Haramis, A.G., Vink, S.C., Vijver, M.G., Schaaf, M.J.M., Tudorache, C. (2019) Polystyrene nanoplastics disrupt glucose metabolism and cortisol levels with a possible link to behavioural changes in larval zebrafish. Communications biology. 2:382
Campbell, C., Su, T., Lau, R.P., Shah, A., Laurie, P.C., Avalos, B., Aggio, J., Harris, E., Traver, D., Stachura, D.L. (2015) Zebrafish Embryonic Stromal Trunk (ZEST) cells support hematopoietic stem and progenitor cell (HSPC) proliferation, survival, and differentiation. Experimental hematology. 43(12):1047-61
Ceinos, R.M., Torres-Nuñez, E., Chamorro, R., Novoa, B., Figueras, A., Ruane, N.M., and Rotllant, J. (2013) Critical Role of the Matricellular Protein SPARC in Mediating Erythroid Progenitor Cell Development in Zebrafish. Cells, tissues, organs. 197(3):196-208
Chen, S., Oikonomou, G., Chiu, C.N., Niles, B.J., Liu, J., Lee, D.A., Antoshechkin, I., and Prober, D.A. (2013) A large-scale in vivo analysis reveals that TALENs are significantly more mutagenic than ZFNs generated using context-dependent assembly. Nucleic acids research. 41(4):2769-2778
Cudak, N., López-Delgado, A.C., Keil, S., Knopf, F. (2023) Fibroblast growth factor pathway component expression in the regenerating zebrafish fin. Gene expression patterns : GEP. 48:119307
Dandin, E., Üstündağ, Ü.V., Ünal, İ., Ateş-Kalkan, P.S., Cansız, D., Beler, M., Ak, E., Alturfan, A.A., Emekli-Alturfan, E. (2022) Stevioside ameliorates hyperglycemia and glucose intolerance, in a diet-induced obese zebrafish model, through epigenetic, oxidative stress and inflammatory regulation. Obesity research & clinical practice. 16(1):23-29
Enya, S., Kawakami, K., Suzuki, Y., Kawaoka, S. (2018) A novel zebrafish intestinal tumor model reveals a role for
cyp7a1
-dependent tumor-liver crosstalk in causing adverse effects on the host.. Disease models & mechanisms. 11(8)
Fan, X., Hou, T., Sun, T., Zhu, L., Zhang, S., Tang, K., Wang, Z. (2019) Starvation stress affects the maternal development and larval fitness in zebrafish (Danio rerio). The Science of the total environment. 695:133897
Gallegos, T.F., Kamei, C.N., Rohly, M., Drummond, I.A. (2019) Fibroblast growth factor signaling mediates progenitor cell aggregation and nephron regeneration in the adult zebrafish kidney. Developmental Biology. 454(1):44-51
Itoh, N. and Konishi, M. (2007) The Zebrafish fgf Family. Zebrafish. 4(3):179-186
Lebedeva, S., de Jesus Domingues, A.M., Butter, F., Ketting, R.F. (2017) Characterization of genetic loss-of-function of Fus in zebrafish. RNA Biology. 14(1):29-35
Lin, C., Lin, C.N., Wang, Y.C., Liu, F.Y., Chien, Y.W., Chuang, Y.J., Lan, C.Y., Hsieh, W.P., Chen, B.S. (2014) Robustness analysis on interspecies interaction network for iron and glucose competition between Candida albicans and zebrafish during infection. BMC systems biology. 8 Suppl 5:S6
Légaré, V.P., Rampal, C.J., Gurberg, T.J.N., Aaltonen, M.J., Janer, A., Zinman, L., Shoubridge, E.A., Armstrong, G.A.B. (2023) Loss of mitochondrial Chchd10 or Chchd2 in zebrafish leads to an ALS-like phenotype and Complex I deficiency independent of the mitochondrial integrated stress response. Developmental Neurobiology. 83(1-2):54-69
Mangos, S., Amaral, A.P., Faul, C., Jüppner, H., Reiser, J., and Wolf, M. (2012) Expression of fgf23 and alphaklotho in developing embryonic tissues and adult kidney of the zebrafish, Danio rerio. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 27(12):4314-4322
Shibata, E., Yokota, Y., Horita, N., Kudo, A., Abe, G., Kawakami, K., Kawakami, A. (2016) Fgf signalling controls diverse aspects of fin regeneration. Development (Cambridge, England). 143:2920-9
Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
Wolf, A., Aggio, J., Campbell, C., Wright, F., Marquez, G., Traver, D., Stachura, D.L. (2017) Zebrafish Caudal Haematopoietic Embryonic Stromal Tissue (CHEST) Cells Support Haematopoiesis. Scientific Reports. 7:44644
Yamauchi, H., Hotta, Y., Konishi, M., Miyake, A., Kawahara, A., and Itoh, N. (2006) Fgf21 is essential for haematopoiesis in zebrafish. EMBO reports. 7(6):649-654
Zhang, H., Wang, X., Lv, K., Gao, S., Wang, G., Fan, C., Zhang, X.A., Yan, J. (2015) Time Point-based Integrative Analyses of Deep-transcriptome Identify Four Signal Pathways in Blastemal Regeneration of Zebrafish Lower Jaw. Stem cells (Dayton, Ohio). 33(3):806-18
Cudak, N., López-Delgado, A.C., Keil, S., Knopf, F. (2023) Fibroblast growth factor pathway component expression in the regenerating zebrafish fin. Gene expression patterns : GEP. 48:119307
Légaré, V.P., Rampal, C.J., Gurberg, T.J.N., Aaltonen, M.J., Janer, A., Zinman, L., Shoubridge, E.A., Armstrong, G.A.B. (2023) Loss of mitochondrial Chchd10 or Chchd2 in zebrafish leads to an ALS-like phenotype and Complex I deficiency independent of the mitochondrial integrated stress response. Developmental Neurobiology. 83(1-2):54-69
Beler, M., Cansız, D., Ünal, İ., Üstündağ, Ü.V., Dandin, E., Ak, E., Alturfan, A.A., Emekli-Alturfan, E. (2022) Bisphenol A reveals its obesogenic effects through disrupting glucose tolerance, oxidant-antioxidant balance, and modulating inflammatory cytokines and fibroblast growth factor in zebrafish. Toxicology and industrial health. 38:19-28
Dandin, E., Üstündağ, Ü.V., Ünal, İ., Ateş-Kalkan, P.S., Cansız, D., Beler, M., Ak, E., Alturfan, A.A., Emekli-Alturfan, E. (2022) Stevioside ameliorates hyperglycemia and glucose intolerance, in a diet-induced obese zebrafish model, through epigenetic, oxidative stress and inflammatory regulation. Obesity research & clinical practice. 16(1):23-29
Blanco, A.M., Bertucci, J.I., Unniappan, S. (2020) FGF21 Mimics a Fasting-Induced Metabolic State and Increases Appetite in Zebrafish. Scientific Reports. 10:6993
Brun, N.R., van Hage, P., Hunting, E.R., Haramis, A.G., Vink, S.C., Vijver, M.G., Schaaf, M.J.M., Tudorache, C. (2019) Polystyrene nanoplastics disrupt glucose metabolism and cortisol levels with a possible link to behavioural changes in larval zebrafish. Communications biology. 2:382
Fan, X., Hou, T., Sun, T., Zhu, L., Zhang, S., Tang, K., Wang, Z. (2019) Starvation stress affects the maternal development and larval fitness in zebrafish (Danio rerio). The Science of the total environment. 695:133897
Gallegos, T.F., Kamei, C.N., Rohly, M., Drummond, I.A. (2019) Fibroblast growth factor signaling mediates progenitor cell aggregation and nephron regeneration in the adult zebrafish kidney. Developmental Biology. 454(1):44-51
Enya, S., Kawakami, K., Suzuki, Y., Kawaoka, S. (2018) A novel zebrafish intestinal tumor model reveals a role for
cyp7a1
-dependent tumor-liver crosstalk in causing adverse effects on the host.. Disease models & mechanisms. 11(8)
Lebedeva, S., de Jesus Domingues, A.M., Butter, F., Ketting, R.F. (2017) Characterization of genetic loss-of-function of Fus in zebrafish. RNA Biology. 14(1):29-35
Wolf, A., Aggio, J., Campbell, C., Wright, F., Marquez, G., Traver, D., Stachura, D.L. (2017) Zebrafish Caudal Haematopoietic Embryonic Stromal Tissue (CHEST) Cells Support Haematopoiesis. Scientific Reports. 7:44644
Shibata, E., Yokota, Y., Horita, N., Kudo, A., Abe, G., Kawakami, K., Kawakami, A. (2016) Fgf signalling controls diverse aspects of fin regeneration. Development (Cambridge, England). 143:2920-9
Campbell, C., Su, T., Lau, R.P., Shah, A., Laurie, P.C., Avalos, B., Aggio, J., Harris, E., Traver, D., Stachura, D.L. (2015) Zebrafish Embryonic Stromal Trunk (ZEST) cells support hematopoietic stem and progenitor cell (HSPC) proliferation, survival, and differentiation. Experimental hematology. 43(12):1047-61
Zhang, H., Wang, X., Lv, K., Gao, S., Wang, G., Fan, C., Zhang, X.A., Yan, J. (2015) Time Point-based Integrative Analyses of Deep-transcriptome Identify Four Signal Pathways in Blastemal Regeneration of Zebrafish Lower Jaw. Stem cells (Dayton, Ohio). 33(3):806-18
Lin, C., Lin, C.N., Wang, Y.C., Liu, F.Y., Chien, Y.W., Chuang, Y.J., Lan, C.Y., Hsieh, W.P., Chen, B.S. (2014) Robustness analysis on interspecies interaction network for iron and glucose competition between Candida albicans and zebrafish during infection. BMC systems biology. 8 Suppl 5:S6
Ceinos, R.M., Torres-Nuñez, E., Chamorro, R., Novoa, B., Figueras, A., Ruane, N.M., and Rotllant, J. (2013) Critical Role of the Matricellular Protein SPARC in Mediating Erythroid Progenitor Cell Development in Zebrafish. Cells, tissues, organs. 197(3):196-208
Chen, S., Oikonomou, G., Chiu, C.N., Niles, B.J., Liu, J., Lee, D.A., Antoshechkin, I., and Prober, D.A. (2013) A large-scale in vivo analysis reveals that TALENs are significantly more mutagenic than ZFNs generated using context-dependent assembly. Nucleic acids research. 41(4):2769-2778
Mangos, S., Amaral, A.P., Faul, C., Jüppner, H., Reiser, J., and Wolf, M. (2012) Expression of fgf23 and alphaklotho in developing embryonic tissues and adult kidney of the zebrafish, Danio rerio. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 27(12):4314-4322
Itoh, N. and Konishi, M. (2007) The Zebrafish fgf Family. Zebrafish. 4(3):179-186
Yamauchi, H., Hotta, Y., Konishi, M., Miyake, A., Kawahara, A., and Itoh, N. (2006) Fgf21 is essential for haematopoiesis in zebrafish. EMBO reports. 7(6):649-654
Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
Additional Citations (14):
Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.
Ensembl curators, GOA curators (2006) Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara. Manually curated data.
Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.
UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.
Zebrafish Nomenclature Committee (2020) Nomenclature Data Curation (2020). Nomenclature Committee Submission.
ZFIN Staff (2017) UniProt ID Load from Ensembl. Semi-automated Curation.
ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.
ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.
ZFIN Staff (2015) Data Model Change: Sequence Targeting Reagents Removed from Environment. ZFIN Historical Data.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.
ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.
ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.
ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.
Zebrafish Nomenclature Committee (2020) Nomenclature Data Curation (2020). Nomenclature Committee Submission.
ZFIN Staff (2017) UniProt ID Load from Ensembl. Semi-automated Curation.
ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
ZFIN Staff (2015) Data Model Change: Sequence Targeting Reagents Removed from Environment. ZFIN Historical Data.
Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.
ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.
UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.
Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.
Ensembl curators, GOA curators (2006) Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara. Manually curated data.
ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.
ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.
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