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ZFIN ID:
ZDB-GENE-040219-13
CITATIONS
(29 total)
Gene Name:
toll-like receptor 8a
Gene Symbol:
tlr8a
Dhanagovind, P.T., Kujur, P.K., Swain, R.K., Banerjee, S. (2021) IL-6 Signaling Protects Zebrafish Larvae during
Staphylococcus epidermidis
Infection in a Bath Immersion Model. Journal of immunology (Baltimore, Md. : 1950). 207(8):2129-2142
Jault, C., Pichon, L., and Chluba, J. (2004) Toll-like receptor gene family and TIR-domain adapters in Danio rerio. Molecular immunology. 40(11):759-771
Kavaliauskis, A., Arnemo, M., Kim, S.H., Ulanova, L., Speth, M., Novoa, B., Dios, S., Evensen, Ø., Griffiths, G.W., Gjøen, T. (2015) Use of Poly(I:C) Stabilized with Chitosan As a Vaccine-Adjuvant Against Viral Hemorrhagic Septicemia Virus Infection in Zebrafish. Zebrafish. 12(6):421-31
Kavaliauskis, A., Arnemo, M., Speth, M.T., Lagos, L., Rishovd, A.L., Estepa, A., Griffiths, G., Gjøen, T. (2016) Protective effect of a recombinant VHSV-G vaccine using poly(I:C) loaded nanoparticles as an adjuvant in zebrafish (Danio rerio) infection model. Developmental and comparative immunology. 61:248-57
Lee, P.T., Zou, J., Holland, J.W., Martin, S.A., Kanellos, T., and Secombes, C.J. (2013) Identification and characterization of TLR7, TLR8a2, TLR8b1 and TLR8b2 genes in Atlantic salmon (Salmo salar). Developmental and comparative immunology. 41(2):295-305
Liu, C., Su, G., Giesy, J.P., Letcher, R.J., Li, G., Agrawal, I., Li, J., Yu, L., Wang, J., Gong, Z. (2016) Acute Exposure to Tris(1,3-dichloro-2-propyl) Phosphate (TDCIPP) Causes Hepatic Inflammation and Leads to Hepatotoxicity in Zebrafish. Scientific Reports. 6:19045
Meijer, A.H., Gabby Krens, S.F., Medina Rodriguez, I.A., He, S., Bitter, W., Snaar-Jagalska, Ewa B., and Spaink, H.P. (2004) Expression analysis of the Toll-like receptor and TIR domain adaptor families of zebrafish. Molecular immunology. 40(11):773-783
Palti, Y., Gahr, S.A., Purcell, M.K., Hadidi, S., Rexroad, C.E. 3rd, and Wiens, G.D. (2010) Identification, characterization and genetic mapping of TLR7, TLR8a1 and TLR8a2 genes in rainbow trout (Oncorhynchus mykiss). Developmental and comparative immunology. 34(2):219-233
Phelps, H.A., and Neely, M.N. (2005) Evolution of the Zebrafish Model: From Development to Immunity and Infectious Disease. Zebrafish. 2(2):87-103
Pietretti, D., Scheer, M., Fink, I.R., Taverne, N., Savelkoul, H.F., Spaink, H.P., Forlenza, M., and Wiegertjes, G.F. (2014) Identification and functional characterization of nonmammalian Toll-like receptor 20. Immunogenetics. 66(2):123-141
Shan, S., Liu, R., Feng, H., Meng, F., Aizaz, M., Yang, G. (2021) Identification and functional characterization of a fish-specific tlr19 in common carp (Cyprinus carpio L.) that recruits TRIF as an adaptor and induces ifn expression during the immune response. Veterinary research. 52:88
Shan, S., Liu, R., Jiang, L., Zhu, Y., Li, H., Xing, W., Yang, G. (2018) Carp Toll-like receptor 8 (Tlr8): An intracellular Tlr that recruits TIRAP as adaptor and activates AP-1 pathway in immune response. Fish & shellfish immunology. 82:41-49
van der Sar, A.M., Stockhammer, O.W., van der Laan, C., Spaink, H.P., Bitter, W., and Meijer, A.H. (2006) MyD88 Innate Immune Function in a Zebrafish Embryo Infection Model. Infection and Immunity. 74(4):2436-2441
Varela, M., Romero, A., Dios, S., van der Vaart, M., Figueras, A., Meijer, A.H., Novoa, B. (2014) Cellular Visualization of Macrophage Pyroptosis and Interleukin-1β Release in a Viral Hemorrhagic Infection in Zebrafish Larvae. Journal of virology. 88(20):12026-40
Yeh, D.W., Liu, Y.L., Lo, Y.C., Yuh, C.H., Yu, G.Y., Lo, J.F., Luo, Y., Xiang, R., and Chuang, T.H. (2013) Toll-like receptor 9 and 21 have different ligand recognition profiles and cooperatively mediate activity of CpG-oligodeoxynucleotides in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 110(51):20711-20716
Zhang, C., Zhao, Z., Jia, Y.J., Zhang, P.Q., Sun, Y., Zhou, Y.C., Wang, G.X., Zhu, B. (2023) Rationally Designed Self-Assembling Nanovaccines Elicit Robust Mucosal and Systemic Immunity against Rhabdovirus. ACS applied materials & interfaces. 16(1):228-244
Zhang, C., Zhao, Z., Jia, Y.J., Zhang, P.Q., Sun, Y., Zhou, Y.C., Wang, G.X., Zhu, B. (2023) Rationally Designed Self-Assembling Nanovaccines Elicit Robust Mucosal and Systemic Immunity against Rhabdovirus. ACS applied materials & interfaces. 16(1):228-244
Dhanagovind, P.T., Kujur, P.K., Swain, R.K., Banerjee, S. (2021) IL-6 Signaling Protects Zebrafish Larvae during
Staphylococcus epidermidis
Infection in a Bath Immersion Model. Journal of immunology (Baltimore, Md. : 1950). 207(8):2129-2142
Shan, S., Liu, R., Feng, H., Meng, F., Aizaz, M., Yang, G. (2021) Identification and functional characterization of a fish-specific tlr19 in common carp (Cyprinus carpio L.) that recruits TRIF as an adaptor and induces ifn expression during the immune response. Veterinary research. 52:88
Shan, S., Liu, R., Jiang, L., Zhu, Y., Li, H., Xing, W., Yang, G. (2018) Carp Toll-like receptor 8 (Tlr8): An intracellular Tlr that recruits TIRAP as adaptor and activates AP-1 pathway in immune response. Fish & shellfish immunology. 82:41-49
Kavaliauskis, A., Arnemo, M., Speth, M.T., Lagos, L., Rishovd, A.L., Estepa, A., Griffiths, G., Gjøen, T. (2016) Protective effect of a recombinant VHSV-G vaccine using poly(I:C) loaded nanoparticles as an adjuvant in zebrafish (Danio rerio) infection model. Developmental and comparative immunology. 61:248-57
Liu, C., Su, G., Giesy, J.P., Letcher, R.J., Li, G., Agrawal, I., Li, J., Yu, L., Wang, J., Gong, Z. (2016) Acute Exposure to Tris(1,3-dichloro-2-propyl) Phosphate (TDCIPP) Causes Hepatic Inflammation and Leads to Hepatotoxicity in Zebrafish. Scientific Reports. 6:19045
Kavaliauskis, A., Arnemo, M., Kim, S.H., Ulanova, L., Speth, M., Novoa, B., Dios, S., Evensen, Ø., Griffiths, G.W., Gjøen, T. (2015) Use of Poly(I:C) Stabilized with Chitosan As a Vaccine-Adjuvant Against Viral Hemorrhagic Septicemia Virus Infection in Zebrafish. Zebrafish. 12(6):421-31
Pietretti, D., Scheer, M., Fink, I.R., Taverne, N., Savelkoul, H.F., Spaink, H.P., Forlenza, M., and Wiegertjes, G.F. (2014) Identification and functional characterization of nonmammalian Toll-like receptor 20. Immunogenetics. 66(2):123-141
Varela, M., Romero, A., Dios, S., van der Vaart, M., Figueras, A., Meijer, A.H., Novoa, B. (2014) Cellular Visualization of Macrophage Pyroptosis and Interleukin-1β Release in a Viral Hemorrhagic Infection in Zebrafish Larvae. Journal of virology. 88(20):12026-40
Lee, P.T., Zou, J., Holland, J.W., Martin, S.A., Kanellos, T., and Secombes, C.J. (2013) Identification and characterization of TLR7, TLR8a2, TLR8b1 and TLR8b2 genes in Atlantic salmon (Salmo salar). Developmental and comparative immunology. 41(2):295-305
Yeh, D.W., Liu, Y.L., Lo, Y.C., Yuh, C.H., Yu, G.Y., Lo, J.F., Luo, Y., Xiang, R., and Chuang, T.H. (2013) Toll-like receptor 9 and 21 have different ligand recognition profiles and cooperatively mediate activity of CpG-oligodeoxynucleotides in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 110(51):20711-20716
Palti, Y., Gahr, S.A., Purcell, M.K., Hadidi, S., Rexroad, C.E. 3rd, and Wiens, G.D. (2010) Identification, characterization and genetic mapping of TLR7, TLR8a1 and TLR8a2 genes in rainbow trout (Oncorhynchus mykiss). Developmental and comparative immunology. 34(2):219-233
van der Sar, A.M., Stockhammer, O.W., van der Laan, C., Spaink, H.P., Bitter, W., and Meijer, A.H. (2006) MyD88 Innate Immune Function in a Zebrafish Embryo Infection Model. Infection and Immunity. 74(4):2436-2441
Phelps, H.A., and Neely, M.N. (2005) Evolution of the Zebrafish Model: From Development to Immunity and Infectious Disease. Zebrafish. 2(2):87-103
Jault, C., Pichon, L., and Chluba, J. (2004) Toll-like receptor gene family and TIR-domain adapters in Danio rerio. Molecular immunology. 40(11):759-771
Meijer, A.H., Gabby Krens, S.F., Medina Rodriguez, I.A., He, S., Bitter, W., Snaar-Jagalska, Ewa B., and Spaink, H.P. (2004) Expression analysis of the Toll-like receptor and TIR domain adaptor families of zebrafish. Molecular immunology. 40(11):773-783
Additional Citations (13):
Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.
Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.
Thisse, C., and Thisse, B. (2005) High Throughput Expression Analysis of ZF-Models Consortium Clones. ZFIN Direct Data Submission.
UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.
ZFIN Staff (2022) Electronic Gene Ontology annotations created by ARBA machine learning models. Automated Data Submission.
ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.
ZFIN Staff (2003) Curation of orthology data. Manually curated data.
ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.
ZFIN Staff (2022) Manual Curation of UniProt IDs. Manually curated data.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.
ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.
ZFIN Staff (2022) Manual Curation of UniProt IDs. Manually curated data.
ZFIN Staff (2022) Electronic Gene Ontology annotations created by ARBA machine learning models. Automated Data Submission.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.
ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.
UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.
Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.
Thisse, C., and Thisse, B. (2005) High Throughput Expression Analysis of ZF-Models Consortium Clones. ZFIN Direct Data Submission.
ZFIN Staff (2003) Curation of orthology data. Manually curated data.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.
ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.
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