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ZFIN ID:
ZDB-GENE-030529-3
CITATIONS
(38 total)
Gene Name:
alcohol dehydrogenase 8a
Gene Symbol:
adh8a
Bise, T., de Preux Charles, A.S., Jaźwińska, A. (2019) Ciliary neurotrophic factor stimulates cardioprotection and the proliferative activity in the adult zebrafish heart. NPJ Regenerative medicine. 4:2
Cheng, W., Guo, L., Zhang, Z., Soo, H.M., Wen, C., Wu, W., and Peng, J. (2006) HNF factors form a network to regulate liver-enriched genes in zebrafish. Developmental Biology. 294(2):482-496
Dasmahapatra, A.K., Wang, X., and Haasch, M.L. (2005) Expression of Adh8 mRNA is developmentally regulated in Japanese medaka (Oryzias latipes). Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 140(4):657-664
de Bakker, D.E.M., Bouwman, M., Dronkers, E., Simões, F.C., Riley, P.R., Goumans, M.J., Smits, A.M., Bakkers, J. (2021) Prrx1b restricts fibrosis and promotes Nrg1-dependent cardiomyocyte proliferation during zebrafish heart regeneration. Development (Cambridge, England). 148(19):
Grinberg, L., Dabbah Assadi, F., Baum, G., Zemel, R., Tur-Kaspa, R., Shochat, C., Karasik, D., Karpuj, M.V. (2023) Beneficial Effect of Vitamin D on Non-Alcoholic Fatty Liver Disease (NAFLD) Progression in the Zebrafish Model. Nutrients. 15(6):
Han, S.C., Huang, R.P., Zhang, Q.Y., Yan, C.Y., Li, X.Y., Li, Y.F., He, R.R., Li, W.X. (2023) Antialcohol and Hepatoprotective Effects of Tamarind Shell Extract on Ethanol-Induced Damage to HepG2 Cells and Animal Models. Foods (Basel, Switzerland). 12(5):
Klüver, N., Ortmann, J., Paschke, H., Renner, P., Ritter, A.P., Scholz, S. (2014) Transient overexpression of adh8a increases allyl alcohol toxicity in zebrafish embryos. PLoS One. 9:e90619
Lam, S.H., Mathavan, S., Tong, Y., Li, H., Karuturi, R.K., Wu, Y., Vega, V.B., Liu, E.T., and Gong, Z. (2008) Zebrafish whole-adult-organism chemogenomics for large-scale predictive and discovery chemical biology. PLoS Genetics. 4(7):e1000121
Lam, S.H., Ung, C.Y., Hlaing, M.M., Hu, J., Li, Z.H., Mathavan, S., and Gong, Z. (2013) Molecular insights into 4-nitrophenol-induced hepatotoxicity in zebrafish: Transcriptomic, histological and targeted gene expression analyses. Biochimica et biophysica acta. General subjects. 1830(10):4778-4789
Levi, L., Ziv, T., Admon, A., Levavi-Sivan, B., and Lubzens, E. (2012) Insight into molecular pathways of retinal metabolism, associated with vitellogenesis in zebrafish. American journal of physiology. Endocrinology and metabolism. 302(6):E626-644
Li, Y., Agrawal, I., Gong, Z. (2019) Reversion of tumor hepatocytes to normal hepatocytes during liver tumor regression in an oncogene transgenic zebrafish model. Disease models & mechanisms. 12(10):
Liu, C., Xu, H., Lam, S.H., and Gong, Z. (2013) Selection of Reliable Biomarkers from PCR Array Analyses Using Relative Distance Computational Model: Methodology and Proof-of-Concept Study. PLoS One. 8(12):e83954
Liu, Y.S., Yuan, M.H., Zhang, C.Y., Liu, H.M., Liu, J.R., Wei, A.L., Ye, Q., Zeng, B., Li, M.F., Guo, Y.P., Guo, L. (2020) Puerariae Lobatae radix flavonoids and puerarin alleviate alcoholic liver injury in zebrafish by regulating alcohol and lipid metabolism. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 134:111121
Nolte, H., Konzer, A., Ruhs, A., Jungblut, B., Braun, T., Krüger, M. (2014) Global protein expression profiling of zebrafish organs based on in vivo incorporation of stable isotopes. Journal of Proteome Research. 13:2162-74
Rabinowitz, J.S., Robitaille, A.M., Wang, Y., Ray, C.A., Thummel, R., Gu, H., Djukovic, D., Raftery, D., Berndt, J.D., Moon, R.T. (2017) Transcriptomic, proteomic, and metabolomic landscape of positional memory in the caudal fin of zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 114(5):E717-E726
Reimers, M.J., Hahn, M.E., and Tanguay, R.L. (2004) Two zebrafish alcohol dehydrogenases share common ancestry with mammalian class I, II, IV, and V ADH genes but have distinct functional characteristics. The Journal of biological chemistry. 279(37):38303-38312
Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
Tsedensodnom, O., Vacaru, A.M., Howarth, D.L., Yin, C., and Sadler, K.C. (2013) Ethanol metabolism and oxidative stress are required for unfolded protein response activation and steatosis in zebrafish with alcoholic liver disease. Disease models & mechanisms. 6(5):1213-26
van der Ven, L.T.M., Schoonen, W.G., Groot, R.M., den Ouden, F., Heusinkveld, H.J., Zwart, E.P., Hodemaekers, H.M., Rorije, E., de Knecht, J. (2020) The effects of aliphatic alcohols and related acid metabolites in zebrafish embryos - correlations with rat developmental toxicity and with effects in advanced life stages in fish. Toxicology and applied pharmacology. 407:115249
Vera, L.M., Bello, C., Paredes, J.F., Carmona-Antoñanzas, G., Sánchez-Vázquez, F.J. (2018) Ethanol toxicity differs depending on the time of day. PLoS One. 13:e0190406
Weeks, O., Miller, B.M., Pepe-Mooney, B.J., Oderberg, I.M., Freeburg, S.H., Smith, C.J., North, T.E., Goessling, W. (2022) Embryonic alcohol exposure disrupts the ubiquitin-proteasome system. JCI insight. 7(23):
Xiao, Y., Jiang, J., Hu, W., Zhao, Y., Hu, J. (2017) Toxicity of triphenyltin on the development of retinal axons in zebrafish at low dose. Aquatic toxicology (Amsterdam, Netherlands). 189:9-15
Grinberg, L., Dabbah Assadi, F., Baum, G., Zemel, R., Tur-Kaspa, R., Shochat, C., Karasik, D., Karpuj, M.V. (2023) Beneficial Effect of Vitamin D on Non-Alcoholic Fatty Liver Disease (NAFLD) Progression in the Zebrafish Model. Nutrients. 15(6):
Han, S.C., Huang, R.P., Zhang, Q.Y., Yan, C.Y., Li, X.Y., Li, Y.F., He, R.R., Li, W.X. (2023) Antialcohol and Hepatoprotective Effects of Tamarind Shell Extract on Ethanol-Induced Damage to HepG2 Cells and Animal Models. Foods (Basel, Switzerland). 12(5):
Weeks, O., Miller, B.M., Pepe-Mooney, B.J., Oderberg, I.M., Freeburg, S.H., Smith, C.J., North, T.E., Goessling, W. (2022) Embryonic alcohol exposure disrupts the ubiquitin-proteasome system. JCI insight. 7(23):
de Bakker, D.E.M., Bouwman, M., Dronkers, E., Simões, F.C., Riley, P.R., Goumans, M.J., Smits, A.M., Bakkers, J. (2021) Prrx1b restricts fibrosis and promotes Nrg1-dependent cardiomyocyte proliferation during zebrafish heart regeneration. Development (Cambridge, England). 148(19):
Liu, Y.S., Yuan, M.H., Zhang, C.Y., Liu, H.M., Liu, J.R., Wei, A.L., Ye, Q., Zeng, B., Li, M.F., Guo, Y.P., Guo, L. (2020) Puerariae Lobatae radix flavonoids and puerarin alleviate alcoholic liver injury in zebrafish by regulating alcohol and lipid metabolism. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 134:111121
van der Ven, L.T.M., Schoonen, W.G., Groot, R.M., den Ouden, F., Heusinkveld, H.J., Zwart, E.P., Hodemaekers, H.M., Rorije, E., de Knecht, J. (2020) The effects of aliphatic alcohols and related acid metabolites in zebrafish embryos - correlations with rat developmental toxicity and with effects in advanced life stages in fish. Toxicology and applied pharmacology. 407:115249
Bise, T., de Preux Charles, A.S., Jaźwińska, A. (2019) Ciliary neurotrophic factor stimulates cardioprotection and the proliferative activity in the adult zebrafish heart. NPJ Regenerative medicine. 4:2
Li, Y., Agrawal, I., Gong, Z. (2019) Reversion of tumor hepatocytes to normal hepatocytes during liver tumor regression in an oncogene transgenic zebrafish model. Disease models & mechanisms. 12(10):
Vera, L.M., Bello, C., Paredes, J.F., Carmona-Antoñanzas, G., Sánchez-Vázquez, F.J. (2018) Ethanol toxicity differs depending on the time of day. PLoS One. 13:e0190406
Rabinowitz, J.S., Robitaille, A.M., Wang, Y., Ray, C.A., Thummel, R., Gu, H., Djukovic, D., Raftery, D., Berndt, J.D., Moon, R.T. (2017) Transcriptomic, proteomic, and metabolomic landscape of positional memory in the caudal fin of zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 114(5):E717-E726
Xiao, Y., Jiang, J., Hu, W., Zhao, Y., Hu, J. (2017) Toxicity of triphenyltin on the development of retinal axons in zebrafish at low dose. Aquatic toxicology (Amsterdam, Netherlands). 189:9-15
Klüver, N., Ortmann, J., Paschke, H., Renner, P., Ritter, A.P., Scholz, S. (2014) Transient overexpression of adh8a increases allyl alcohol toxicity in zebrafish embryos. PLoS One. 9:e90619
Nolte, H., Konzer, A., Ruhs, A., Jungblut, B., Braun, T., Krüger, M. (2014) Global protein expression profiling of zebrafish organs based on in vivo incorporation of stable isotopes. Journal of Proteome Research. 13:2162-74
Lam, S.H., Ung, C.Y., Hlaing, M.M., Hu, J., Li, Z.H., Mathavan, S., and Gong, Z. (2013) Molecular insights into 4-nitrophenol-induced hepatotoxicity in zebrafish: Transcriptomic, histological and targeted gene expression analyses. Biochimica et biophysica acta. General subjects. 1830(10):4778-4789
Liu, C., Xu, H., Lam, S.H., and Gong, Z. (2013) Selection of Reliable Biomarkers from PCR Array Analyses Using Relative Distance Computational Model: Methodology and Proof-of-Concept Study. PLoS One. 8(12):e83954
Tsedensodnom, O., Vacaru, A.M., Howarth, D.L., Yin, C., and Sadler, K.C. (2013) Ethanol metabolism and oxidative stress are required for unfolded protein response activation and steatosis in zebrafish with alcoholic liver disease. Disease models & mechanisms. 6(5):1213-26
Levi, L., Ziv, T., Admon, A., Levavi-Sivan, B., and Lubzens, E. (2012) Insight into molecular pathways of retinal metabolism, associated with vitellogenesis in zebrafish. American journal of physiology. Endocrinology and metabolism. 302(6):E626-644
Lam, S.H., Mathavan, S., Tong, Y., Li, H., Karuturi, R.K., Wu, Y., Vega, V.B., Liu, E.T., and Gong, Z. (2008) Zebrafish whole-adult-organism chemogenomics for large-scale predictive and discovery chemical biology. PLoS Genetics. 4(7):e1000121
Cheng, W., Guo, L., Zhang, Z., Soo, H.M., Wen, C., Wu, W., and Peng, J. (2006) HNF factors form a network to regulate liver-enriched genes in zebrafish. Developmental Biology. 294(2):482-496
Dasmahapatra, A.K., Wang, X., and Haasch, M.L. (2005) Expression of Adh8 mRNA is developmentally regulated in Japanese medaka (Oryzias latipes). Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 140(4):657-664
Reimers, M.J., Hahn, M.E., and Tanguay, R.L. (2004) Two zebrafish alcohol dehydrogenases share common ancestry with mammalian class I, II, IV, and V ADH genes but have distinct functional characteristics. The Journal of biological chemistry. 279(37):38303-38312
Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
Additional Citations (16):
Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.
Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.
ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.
ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.
ZFIN Staff (2002) Scientific Curation. Manually curated data.
ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.
ZFIN Staff (2003) Curation of unpublished nucleotide sequence accession numbers. Manually curated data.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.
ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.
ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.
ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.
ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.
ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.
ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.
ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.
ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.
ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.
Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.
ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.
ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.
ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.
ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.
ZFIN Staff (2003) Curation of unpublished nucleotide sequence accession numbers. Manually curated data.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.
ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.
ZFIN Staff (2002) Scientific Curation. Manually curated data.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.
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