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Phenotype Figure Summary
Marker:
tmem67
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Wang
et al.
, 2022
Fig. 1.
tmem67
uab14/uab14
(AB)
post-vent region curved ventral, abnormal
vertebral column increased curvature, abnormal
Fig. 2.
tmem67
uab14/uab14
(AB)
vertebral column increased curvature, abnormal
Fig. 4.
tmem67
uab14/uab14
(AB)
retina inflammatory response increased occurrence, abnormal
retinal cone cell photoreceptor outer segment decreased amount, abnormal
retinal outer nuclear layer cell population proliferation increased occurrence, abnormal
Fig. 6.
tmem67
uab14/uab14
(AB)
post-vent region curved ventral, abnormal
post-vent region increased curvature, abnormal
text only
tmem67
uab14/uab14
(AB)
female organism female sterile, abnormal
male organism male sterile, abnormal
Lee
et al.
, 2017
Fig. 3
AB + MO4-tmem67
fourth ventricle increased size, abnormal
hindbrain hydrocephalic, abnormal
Fig. 4
kyu1Tg + MO4-tmem67
, 
AB + MO4-tmem67
brain
axin2
expression decreased amount, abnormal
brain d2EGFP expression decreased amount, abnormal
whole organism
axin2
expression decreased amount, abnormal
Wnt signaling pathway disrupted, abnormal
Fig. S2
AB + MO1-tmem67
fourth ventricle increased size, abnormal
hindbrain hydrocephalic, abnormal
Stayner
et al.
, 2017
Fig. 5
AB + MO1-tmem67
brain morphology, abnormal
notochord kinked, abnormal
notochord morphology, abnormal
otic placode morphology, abnormal
somite increased width, abnormal
whole organism anterior-posterior axis shortened, abnormal
Leightner
et al.
, 2013
Fig. 7
WT + MO2-tmem67
, 
WT + MO3-tmem67
head hydrocephalic, abnormal
pronephros cystic, abnormal
whole organism increased curvature, abnormal
Fig. 8
WT + MO2-tmem67
convergent extension involved in axis elongation disrupted, abnormal
Fig. 9
WT + MO3-tmem67
cilium movement decreased frequency, abnormal
pronephric duct cilium decreased functionality, abnormal
Adams
et al.
, 2012
Fig. 5
WT + MO1-tmem67
cilium assembly decreased process quality, abnormal
notochord malformed, abnormal
Fig. S5
WT + MO1-tmem67
brain malformed, abnormal
cilium assembly decreased process quality, abnormal
eye decreased size, abnormal
eye malformed, abnormal
head lacks parts or has fewer parts of type otic placode, abnormal
notochord malformed, abnormal
pronephros cystic, abnormal
Valente
et al.
, 2010
Fig. 5
WT + MO1-tmem67
notochord increased width, abnormal
somite morphology, abnormal
whole organism anterior-posterior axis decreased length, abnormal
Leitch
et al.
, 2008
Fig. 3
WT + MO1-tmem67
notochord undulate, abnormal
somite deformed, abnormal
whole organism decreased length, abnormal
whole organism decreased life span, abnormal
whole organism decreased thickness, abnormal
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