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Phenotype Figure Summary
Marker:
exoc5
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Rohrer
et al.
, 2021
Figure 1
exoc5
sa23168/sa23168
(AB/TU)
eye decreased size, abnormal
retinal photoreceptor layer decreased thickness, abnormal
retinal photoreceptor layer photoreceptor outer segment decreased length, abnormal
retinal pigment epithelium development decreased process quality, abnormal
retinal pigmented epithelium decreased thickness, abnormal
retinal pigmented epithelium has fewer parts of type retinal pigmented epithelium melanosome, abnormal
Figure 2
exoc5
sa23168/sa23168
(AB/TU)
retinal cone cell cone photoreceptor outer segment decreased length, abnormal
retinal cone cell cone photoreceptor outer segment malformed, abnormal
retinal cone cell photoreceptor cell outer segment organization decreased process quality, abnormal
retinal rod cell photoreceptor cell outer segment organization decreased process quality, abnormal
retinal rod cell rod photoreceptor outer segment decreased length, abnormal
Figure 3
exoc5
sa23168/sa23168
; fl1Tg (AB/TU)
retinal cone cell photoreceptor cell outer segment organization decreased process quality, abnormal
retinal rod cell photoreceptor cell outer segment organization decreased process quality, abnormal
Fulmer
et al.
, 2019
Fig. 1
exoc5
sa23168/sa23168
brain hydrocephalic, abnormal
bulbus arteriosus constricted, abnormal
eye decreased size, abnormal
pericardium edematous, abnormal
whole organism
exoc4
expression decreased amount, abnormal
whole organism dead, abnormal
whole organism decreased life span, abnormal
Fig. S6
exoc5
uab3/uab3
brain hydrocephalic, abnormal
bulbus arteriosus constricted, abnormal
eye decreased size, abnormal
pericardium edematous, abnormal
whole organism
exoc4
expression decreased amount, abnormal
Zuo
et al.
, 2019
Fig. 4
exoc5
sa23168/sa23168
caudal fin curved, abnormal
eye decreased size, abnormal
pericardium edematous, abnormal
whole organism Ab1-exoc4 labeling decreased amount, abnormal
whole organism Ab1-mob1 labeling increased amount, abnormal
Lobo
et al.
, 2017
Fig. 1
exoc5
sa23168/sa23168
brain hydrocephalic, abnormal
eye decreased size, abnormal
pericardium edematous, abnormal
post-vent region curved, abnormal
regulation of hippo signaling disrupted, abnormal
whole organism Ab1-mob1 labeling increased amount, abnormal
Fig. 2
exoc5
sa23168/sa23168
photoreceptor outer segment layer disorganized, abnormal
retina layer formation disrupted, abnormal
retinal cone cell photoreceptor outer segment decreased amount, abnormal
retinal cone cell photoreceptor outer segment decreased length, abnormal
Fig. 3
exoc5
sa23168/sa23168
photoreceptor outer segment layer photoreceptor outer segment disorganized, abnormal
photoreceptor outer segment layer photoreceptor outer segment morphology, abnormal
retina cilium absent, abnormal
retinal cone cell photoreceptor outer segment decreased length, abnormal
retinal rod cell photoreceptor outer segment decreased length, abnormal
Fig. S1
exoc5
uab3/uab3
brain hydrocephalic, abnormal
eye decreased size, abnormal
pericardium edematous, abnormal
post-vent region curved, abnormal
Choi
et al.
, 2015
Fig. 1
WT + MO1-exoc5
eye decreased size, abnormal
Fig. 2
WT + MO1-exoc5
retina cell decreased amount, abnormal
retina decreased size, abnormal
retinal outer nuclear layer absent, abnormal
Fig. 3
WT + MO1-exoc5
retina apoptotic process increased occurrence, abnormal
retina apoptotic, abnormal
retinal ganglion cell layer apoptotic, abnormal
retinal inner nuclear layer apoptotic, abnormal
retinal outer nuclear layer apoptotic, abnormal
Fig. 4
WT + MO1-exoc5
photoreceptor cell photoreceptor outer segment absent, abnormal
photoreceptor cell photoreceptor outer segment decreased amount, abnormal
photoreceptor cell photoreceptor outer segment decreased length, abnormal
photoreceptor cell photoreceptor outer segment morphology, abnormal
Fig. 6
WT + MO1-exoc5
melanosome transport delayed, abnormal
Fogelgren
et al.
, 2011
Fig. 3
WT + MO1-exoc5
, 
WT + MO1-exoc5 + MO2-exoc5
pronephric glomerulus disorganized, abnormal
pronephros cilium disorganized, abnormal
Fig. 4
WT + MO1-exoc5
post-vent region curved, abnormal
text only
WT + MO1-exoc5
, 
WT + MO1-exoc5 + MO2-exoc5
determination of left/right symmetry process quality, abnormal
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