ZFIN is now using GRCz12tu for Genomic Data
Gene
exoc5
- ID
- ZDB-GENE-080204-126
- Name
- exocyst complex component 5
- Symbol
- exoc5 Nomenclature History
- Previous Names
-
- sec10 (1)
- zgc:175220
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Acts upstream of or within several processes, including melanosome transport; photoreceptor cell maintenance; and photoreceptor cell outer segment organization. Predicted to be located in cytoplasm. Predicted to be part of exocyst. Used to study bicuspid aortic valve disease. Orthologous to human EXOC5 (exocyst complex component 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 18 figures from 6 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| bicuspid aortic valve disease | exoc5uab3/uab3 | standard conditions | Fulmer et al., 2019 |
| bicuspid aortic valve disease | exoc5sa23168/sa23168 | standard conditions | Fulmer et al., 2019 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Exocyst complex component Sec10-like | Exocyst complex component Sec10-like, alpha-helical bundle | Exocyst complex component Sec10, N-terminal |
|---|---|---|---|---|---|
| UniProtKB:B0BLY0 | InterPro PDB | 708 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers