Publication	Data		Fish	Anatomy
Li et al., 2020	Fig. 3		foxp3aihb419/ihb419 (AB)	female gonad development disrupted, abnormal female organism decreased length, abnormal female organism decreased weight, abnormal male gonad development disrupted, abnormal male organism decreased length, abnormal male organism decreased weight, abnormal ovary decreased size, abnormal ovulation decreased rate, abnormal testis decreased size, abnormal
	Fig. 4		foxp3aihb419/ihb419 (AB)	female gonad development disrupted, abnormal male gonad development delayed, abnormal oocyte degeneration, abnormal oocyte stage III absent, abnormal oocyte stage III decreased amount, abnormal oocyte stage IV decreased amount, abnormal sperm decreased amount, abnormal spermatocyte increased amount, abnormal spermatogonium increased amount, abnormal testis present, abnormal testis structure, abnormal
	Fig. 5		foxp3aihb419/ihb419 (AB)	gonad cyp19a1a expression decreased amount, abnormal gonad ddx4 expression decreased amount, abnormal gonad dmrt1 expression increased amount, abnormal gonad ifng1r expression increased amount, abnormal gonad tnfa expression increased amount, abnormal gonad apoptotic, abnormal testis ddx4 expression decreased amount, abnormal testis ifng1r expression increased amount, abnormal testis tnfa expression increased amount, abnormal testis apoptotic, abnormal
	Fig. 6		foxp3aihb419/ihb419 (AB)	testis amh expression decreased amount, abnormal testis cyp11c1 expression decreased amount, abnormal testis cyp17a1 expression decreased amount, abnormal testis dazl expression decreased amount, abnormal testis ddx4 expression decreased amount, abnormal testis dnd1 expression decreased amount, abnormal testis gsdf expression decreased amount, abnormal testis gsdf expression increased distribution, abnormal testis hsd3b2 expression decreased amount, abnormal testis insl3 expression decreased amount, abnormal testis insl3 expression increased distribution, abnormal testis nanos2 expression decreased amount, abnormal testis nanos3 expression decreased amount, abnormal testis zbtb16a expression decreased amount, abnormal testis Ab2-sycp3 labeling decreased amount, abnormal testis Ab36-h3 labeling decreased amount, abnormal testis apoptotic, abnormal testis male meiotic nuclear division decreased occurrence, abnormal testis mitotic cell cycle decreased occurrence, abnormal
	Fig. 7		foxp3aihb419/ihb419; ihb20Tg (AB) ,   foxp3aihb419/ihb419; cz2Tg (AB) ,   foxp3aihb419/ihb419 (AB)	testis ifng1r expression increased amount, abnormal testis il6 expression increased amount, abnormal testis lck expression increased amount, abnormal testis mpeg1.1 expression increased amount, abnormal testis tnfa expression increased amount, abnormal testis macrophage increased amount, abnormal testis T cell increased amount, abnormal
Kasheta et al., 2017	Fig. 4		foxp3aum253/+; foxp3aum252/+ (AB) ,   foxp3aum253/um253 (AB) ,   foxp3aum252/um252 (AB)	head kidney foxp3b expression decreased amount, abnormal whole organism decreased life span, abnormal
	Fig. 5		foxp3aum252/um252; cz2Tg ,   foxp3aum253/+; foxp3aum252/+ (AB) ,   foxp3aum253/um253 (AB) ,   foxp3aum252/um252 (AB)	cloacal chamber inflammatory response increased occurrence, abnormal head kidney lymphocyte increased amount, abnormal head kidney myeloid cell decreased amount, abnormal integument ifng1 expression decreased amount, abnormal posterior intestine ifng1 expression decreased amount, abnormal posterior intestine il1b expression decreased amount, abnormal spleen increased size, abnormal spleen lymphocyte increased amount, abnormal
Sugimoto et al., 2017	Fig. 1		foxp3avcc6/vcc6	whole organism cd4-1 expression increased amount, abnormal whole organism cd8a expression increased amount, abnormal whole organism eomesa expression increased amount, abnormal whole organism eomesb expression increased amount, abnormal whole organism gata3 expression increased amount, abnormal whole organism ifng1r expression increased amount, abnormal whole organism il17a/f3 expression increased amount, abnormal whole organism il1b expression increased amount, abnormal whole organism il21 expression increased amount, abnormal whole organism il22 expression increased amount, abnormal whole organism il26 expression increased amount, abnormal whole organism il4 expression increased amount, abnormal whole organism il6 expression increased amount, abnormal whole organism lck expression increased amount, abnormal whole organism mpeg1.1 expression increased amount, abnormal whole organism mpx expression increased amount, abnormal whole organism pax5 expression increased amount, abnormal whole organism spi1b expression increased amount, abnormal whole organism tbx21 expression increased amount, abnormal whole organism tnfa expression increased amount, abnormal whole organism decreased length, abnormal whole organism decreased weight, abnormal whole organism viability, abnormal
	Fig. 2		foxp3avcc6/vcc6 ,   foxp3avcc6/vcc6; vcc4Tg/+	gill filament swollen, abnormal gill filament T cell EGFP expression increased amount, abnormal gill has extra parts of type T cell, abnormal gill inflamed, abnormal integument has extra parts of type T cell, abnormal integument inflamed, abnormal integument T cell EGFP expression increased amount, abnormal intestine has extra parts of type T cell, abnormal intestine swollen, abnormal intestine T cell EGFP expression increased amount, abnormal olfactory epithelium has extra parts of type T cell, abnormal olfactory epithelium inflamed, abnormal olfactory epithelium T cell EGFP expression increased amount, abnormal pharynx has extra parts of type T cell, abnormal pharynx inflamed, abnormal pharynx T cell EGFP expression increased amount, abnormal
	Fig. S4		foxp3avcc6/vcc6	whole organism foxp3b expression increased amount, abnormal