Research
Search
Genes / Clones
Expression
Mutants / Tg
Antibodies
Anatomy / GO / Human Disease / Chemical
Publications
Data Mining
Downloads
Data Model
AllianceMine
BioMart
Genomics
BLAST
ZFIN
Ensembl
NCBI
UCSC
Genome Browsers
ZFIN
Ensembl
Vega
GRC
UCSC
NCBI
Resources
Zebrafish Genomics
Other Genome Databases
Resources
General
The Zebrafish Book
Protocol Wiki
Antibody Wiki
Anatomy Atlases
Resources for Students and Educators
Zebrafish Programs
ZF-Health
Husbandry Resources
More...
Resource Centers
Zebrafish International Resource Center (ZIRC)
China Zebrafish Resource Center (CZRC)
European Zebrafish Resource Center (EZRC)
Community
Announcements
News
Meetings
Jobs
Alliance Community Forum
Search
People
Labs
Companies
Societies
International Zebrafish Society (IZFS)
Zebrafish Disease Models Society (ZDMS)
Genetics Society of America (GSA)
Zebrafish Husbandry Association
Support
Nomenclature
Nomenclature Conventions
Line Designations
Wild-Type Lines
Submit a Proposed Gene Name
Submit a Proposed Mutant/Tg Line Name
Publications
Guidelines for Authors
Zebrashare
Citing ZFIN
Using ZFIN
Help & Tips
Glossary
Single Box Search Help
Submit Data
Terms of Use
About Us
About ZFIN
Contact Information
Statistics
Committees
Jobs at ZFIN
Sign In
Phenotype Figure Summary
Marker:
alx1
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Yoon
et al.
, 2022
Fig. 1
alx1
uw2016/uw2016
annular ligament absent, abnormal
eye morphology, abnormal
lens absent, abnormal
lens capsule structure, abnormal
Fig. 2
alx1
uw2016/uw2016
eye
col2a1a
expression absent, abnormal
Fig. 3
alx1
uw2016/uw2016
eye nucleate erythrocyte increased distribution, abnormal
Fig. 8
alx1
uw2016/uw2016
, 
alx1
uw2016/+
, 
alx1
uw2016/uw2016
chondrocranium morphology, abnormal
eye morphology, abnormal
Pini
et al.
, 2020
Fig. 6
alx1
uw2016/uw2016
(NHGRI-1)
chondrocranium cartilage chondrocyte cuboid, abnormal
chondrocranium cartilage morphology, abnormal
embryonic neurocranium morphogenesis process quality, abnormal
ethmoid cartilage decreased size, abnormal
ethmoid cartilage morphology, abnormal
Meckel's cartilage decreased size, abnormal
whole organism
alx1
expression decreased amount, abnormal
whole organism
alx3
expression increased amount, abnormal
whole organism
alx4a
expression increased amount, abnormal
Dee
et al.
, 2013
Fig. 3
WT + MO2-alx1
, 
WT + MO1-alx1
cornea disorganized, abnormal
embryonic camera-type eye morphogenesis decreased process quality, abnormal
embryonic viscerocranium morphogenesis decreased process quality, abnormal
eye decreased size, abnormal
head decreased size, abnormal
heart edematous, abnormal
lens decreased size, abnormal
mandibular arch skeleton absent, abnormal
retinal photoreceptor layer disorganized, abnormal
Fig. 4
WT + MO1-alx1
ceratobranchial cartilage absent, abnormal
embryonic neurocranium morphogenesis decreased process quality, abnormal
embryonic viscerocranium morphogenesis decreased process quality, abnormal
ethmoid cartilage decreased size, abnormal
Meckel's cartilage absent, abnormal
neurocranial trabecula decreased size, abnormal
palatoquadrate cartilage absent, abnormal
Fig. 5
WT + MO1-alx1
cranial neural crest physical object quality, abnormal
neural crest cell development decreased process quality, abnormal
Fig. 6
ba2Tg + MO1-alx1
cranial neural crest physical object quality, abnormal
neural crest cell migration decreased process quality, abnormal
Fig. 7
ba2Tg + MO1-alx1
, 
WT + MO1-alx1
cranial neural crest cell mislocalised, abnormal
embryonic neurocranium morphogenesis decreased process quality, abnormal
neural crest cell migration decreased process quality, abnormal
neurocranial trabecula absent, abnormal
Your Input Welcome
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Name:
Institution:
Email address:
Please leave blank:
Subject:
Comments:
Send your comments
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.