Gene

alx1

ID
ZDB-GENE-050419-191
Name
ALX homeobox 1
Symbol
alx1 Nomenclature History
Previous Names
  • si:ch211-154h20.1
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to have DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in embryonic cranial skeleton morphogenesis and neural crest cell migration. Predicted to localize to nucleus. Is expressed in head; head mesenchyme; neural crest; pectoral fin bud; and presumptive cephalic mesoderm. Orthologous to human ALX1 (ALX homeobox 1).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from Dee et al., 2013
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from Dee et al., 2013
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With alx1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Frontonasal dysplasia 3 613456
Associated With alx1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR003654 OAR domain
Family IPR033209 ALX homeobox protein 1
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length ALX homeobox protein 1 Homeobox, conserved site Homeobox domain Homeobox-like domain superfamily OAR domain
UniProtKB:Q1LVQ7 320
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations