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Phenotype Figure Summary
Marker:
egfl7
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
El-Brolosy
et al.
, 2019
Fig. 1
egfl7
bns303/bns303
whole organism
egfl7
expression decreased amount, abnormal
whole organism
emilin3a
expression increased amount, abnormal
Fig. 3
egfl7
bns302/bns302
; y1Tg
vasculature morphology, abnormal
Fig. S2
egfl7
bns303/bns303
, 
egfl7
bns303/+
whole organism
emilin3a
expression increased amount, abnormal
Lai
et al.
, 2019
Fig. 4
AB + MO1-egfl7
cellular response to stress increased process quality, abnormal
whole organism
casp8
expression increased amount, abnormal
whole organism
isg15
expression increased amount, abnormal
whole organism
isg20
expression increased amount, abnormal
whole organism
phlda3
expression increased amount, abnormal
whole organism
tp53
expression increased amount, abnormal
Rossi
et al.
, 2015
Fig. 1
egfl7
s981/s981
brain hemorrhagic, abnormal
Fig. 2
s843Tg + MO1-egfl7
, 
egfl7
s981/+
; s843Tg + MO1-egfl7
, 
egfl7
s981/s981
; s843Tg + MO1-egfl7
intersegmental vessel morphology, abnormal
intersegmental vessel morphology, ameliorated
pericardium edematous, abnormal
Fig. 3
egfl7
s981/s981
whole organism
emilin2a
expression increased amount, abnormal
whole organism
emilin3a
expression increased amount, abnormal
whole organism
emilin3b
expression increased amount, abnormal
Fig. S5
WT + MO1-egfl7
whole organism
tp53
expression increased amount, abnormal
Fig. S6
s843Tg + CRISPR2-egfl7
, 
s843Tg + CRISPR3-egfl7
blood circulation disrupted, abnormal
intersegmental vessel morphology, abnormal
Fig. S8
egfl7
s981/s981
whole organism
emilin2a
expression increased amount, abnormal
whole organism
emilin3a
expression increased amount, abnormal
whole organism
emilin3b
expression increased amount, abnormal
De Mazière
et al.
, 2008
Fig. 5
s843Tg + MO1-egfl7
axial vasculature decreased area, abnormal
dorsal aorta mislocalised dorsally, abnormal
dorsal aorta unlumenized, abnormal
establishment or maintenance of epithelial cell apical/basal polarity disrupted, abnormal
posterior cardinal vein deformed, abnormal
posterior cardinal vein mislocalised dorsally, abnormal
Fig. 6
s843Tg + MO1-egfl7
blood vessel endothelial cell bicellular tight junction increased amount, abnormal
blood vessel endothelial cell bicellular tight junction mislocalised, abnormal
dorsal aorta blood vessel endothelial cell positional polarity, abnormal
dorsal aorta obstructed, abnormal
establishment or maintenance of epithelial cell apical/basal polarity disrupted, abnormal
Fig. 7
s843Tg + MO1-egfl7
blood vessel endothelial cell bicellular tight junction increased amount, abnormal
blood vessel endothelial cell bicellular tight junction mislocalised, abnormal
posterior cardinal vein blood vessel endothelial cell structure, abnormal
posterior cardinal vein duplicated, abnormal
text only
s843Tg + MO1-egfl7
ventral wall of dorsal aorta deformed, abnormal
Schmidt
et al.
, 2007
Fig. 1
WT + MO1-egfl7
blood vessel endothelial cell migration disrupted, abnormal
blood vessel endothelial cell mislocalised, abnormal
posterior cardinal vein morphology, abnormal
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