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Phenotype Figure Summary
Marker:
igf2b
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Dallinga
et al.
, 2018
Fig. 4
y7Tg + MO2-igf2b + MO3-igf2b + MO4-tp53
intersegmental vessel filopodium decreased amount, abnormal
intersegmental vessel sprouting angiogenesis disrupted, abnormal
Hartnett
et al.
, 2010
Fig. 1
AB + MO3-igf2b
brain structure, abnormal
eye decreased size, abnormal
intermediate cell mass of mesoderm distended, abnormal
somite morphology, abnormal
whole organism decreased length, abnormal
whole organism wholly ventralized, abnormal
Fig. 6
AB + MO3-igf2b
blood circulation disrupted, abnormal
bulbus arteriosus morphology, abnormal
heart increased size, abnormal
heart looping arrested, abnormal
Fig. S4
AB + MO3-igf2b
apoptotic process increased occurrence, abnormal
neural keel apoptotic, abnormal
Fig. S5
AB + MO3-igf2b
dorsal/ventral pattern formation disrupted, abnormal
whole organism wholly ventralized, abnormal
Fig. S6
AB + MO3-igf2b
blood circulation disrupted, abnormal
blood decreased fluid flow, abnormal
post-vent vasculature increased accumulation blood, abnormal
trunk vasculature increased accumulation blood, abnormal
vasculature increased accumulation blood, abnormal
text only
AB + MO3-igf2b
, 
y1Tg + MO3-igf2b
angiogenesis disrupted, abnormal
heart contraction decreased occurrence, abnormal
White
et al.
, 2009
Fig. 3
AB/TU + MO1-igf2b
convergent extension involved in axis elongation delayed, abnormal
dorsal/ventral axis specification disrupted, abnormal
notochord undulate, abnormal
whole organism curved ventral, abnormal
Fig. 4
AB/TU + MO1-igf2b + MO2-igf2b
notochord development delayed, abnormal
notochord undulate, abnormal
somite specification disrupted, abnormal
trunk has fewer parts of type somite, abnormal
Fig. 5
AB/TU + MO1-igf2b + MO2-igf2b
forebrain morphology, abnormal
Fig. 6
AB/TU + MO1-igf2b + MO2-igf2b
pronephric duct medial side fused with pronephric duct medial side, abnormal
renal system process disrupted, abnormal
whole organism edematous, abnormal
text only
AB/TU + MO2-igf2b
, 
AB/TU + MO1-igf2b + MO2-igf2b
convergent extension involved in axis elongation delayed, abnormal
notochord undulate, abnormal
whole organism curved ventral, abnormal
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