FIGURE SUMMARY
- Title
-
A Heat-Shock Protein Axis Regulates VEGFR2 Proteolysis, Blood Vessel Development and Repair
- Authors
- Bruns, A.F., Yuldasheva, N., Latham, A.M., Bao, L., Pellet-Many, C., Frankel, P., Stephen, S.L., Howell, G.J., Wheatcroft, S.B., Kearney, M.T., Zachary, I.C., and Ponnambalam, S.
- Source
- Full text @ PLoS One
Requirement for HSP70 or HSP90 in zebrafish blood vessel development. (A) Fli1-GFP zebrafish embryos injected with control morpholinos or with morpholinos specific for HSP70 or HSP90β followed by vasculature staining for GFP. The results shown are representative of two experiments in each of which at least 100 embryos were injected with each morpholino. CA, Caudal Artery; CV, Caudal Vein; DLAV, Dorsal Longitudinal Anastomotic Vessel; Se, Intersegmental Vessel; DA, Dorsal Aorta; PCV, Posterior Cardinal Vein. (B) HSP70 or (C) HSP90β protein levels determined by immunoblot analysis; tubulin served as a control. |
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ PLoS One