ZFIN ID: ZDB-ALT-170918-20
Genomic Feature: zy52
Synonyms:
Affected Genomic Regions: gdf3 (1)
Type: Small Deletion (1)
Protocol: embryos treated with TALEN1-gdf3
Lab Of Origin: Yost Lab
Location: Chr 17: 4245241 (GRCz11) (1) Details
Sequence:
Current Sources:
MUTATION DETAILS
DNA/cDNA Change: 1 bp deleted in Exon 1 (1)
Transcript Consequence: Frameshift, Premature Stop (2)
FLANKING SEQUENCE (GENOMIC)
GTTGATGGTGAAAAAAGAAATTCTATAAATTGTCCTTTCTTAATACATGGACTTGCTCAACATGTGATGGCTTCATATATATCCCCAATGACTCTTTATAAAAATGCATTTTCCAAATAAAATAAATAAATAATTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAAAATGTAAACATTTTATTATAAATAAATAAATTATAAATAGTCACTTTTTAAGTGTGGTCCGTAAGATCCTCACCTTGATCCTGCATAAACCTCACGATGTTTCCTCGTACCCCATATTCAGACACCACACATGGGTCATTAACGGTCTGTTTGCTGGCCTGTTTAAAGATTTTCCACATCTGTGATGGCACTGCGGCATGATGCGATGGTTTGGGTCGACTCCAGAGTCCCATAGAGCTCAAAAACAGCTTTTCTTGCACAAGACCATCATCTTCTGCA
G/-
GAGAACAGAGACTGAGGGTCAGAAGACAGGCTCTGAGGAGGACCAAGAACATTATTAGATTATAAAAACAGAGCAAAGAACACACACAGGCTTATAAATGCCAGCTGATCAGCTTCACATGGCCAGAAATCCACATCTGCAAGCTGATTGGTGGAGATAAAGGAGTTGATTGATCAGCAGCAGGGGGTGGTGTCATTCACATGCAAATCAGCTCTTTGATGTTTATAGGCATCAGGTTGCCTGGCAGACACAGCTCTGATTTATTGCATGAAGATTTTGGGATCTGCAATGATTTAATAATTAAAATGAGTAGGGGAAAATGCTAAAAATGACTTTTTTATTTGCTTTTTTATTTTATTTTATGAGGGTGATCTGTTTTTTTTTTTTATTTAATTATGACAAAATATTTATATACCGCTACAGACAAAACACTGCAAGTCTCAGTTTTACTGATTTCTGTTTATAAAGGCATCAAATTGACAAGAAAACACACTGATCTG
NOTES
Comment Citation
stop codon early in the pro-domain of Gdf3 Bisgrove et al., 2017
OTHER zy52 PAGES No links to external sites
GENOTYPES
Zygosity Genotype (Background) Affected Genomic Regions Parental Zygosity
Homozygous gdf3zy52/zy52 (AB) gdf3 ♀+/- ♂+/-
gdf3zy52/zy52 (AB) gdf3 ♀-/-

CITATIONS  (2)