Genomic Feature
ct811
- ID
- ZDB-ALT-131122-10
- Name
- ct811
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- embryos treated with zinc finger nuclease
- Lab of Origin
- Prober Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 19: 20113586 - 20113603 (GRCz11) (1) Details
- Nucleotide change
- TCCCGGGTTGTCGGGCT/-
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 17 bp deleted (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
-
TTAGGTTGAAAACTTTGTAATAGTTTTTCTCTATTTCTTTCTAGCTGTCAAAACATTTAAAGAAACAATTGTTGATTTCCTCTCGTCAGTAATTAATTTAATAAGGAAATTCACCAGTTCATTTTTGTAAGTACAAAATCACACCCTGCTGTTTCAACTCGTGAGAGAAACGCTTTTAAAGCACCGCGTAGGGCGCAGTTAATTAGAAACGCGGTGGGGTTTTATCTAAAGGATTAATACCTTGCTTCCGAAAAGAAAGAAAATGAACTATGTGATGTTTGTCCAGTCAACAGCTGCCGCAGTGCCACTTAAGAACATTTAAATGCTAAAACTGCAGTTCAAAATAAATTCATGGCGTTTTGAGGACAGAAACACTTGAGGAAGAATTTGAGACTACGCTAATATTACAAACGAGGAGCTCACCTCTGCCTTGTTATGAGGTTGATGTAGTGTCTTAGTGCTGAATAATACTTGGCGAGCTCCTCCGCAGGTGCGTCCTC
TCCCGGGTTGTCGGGCT/- TGTTGGATACCCTTCTGTGAGAGTCCCCAAGCAGACGAACAAGAGAAACGCGCACGCTGCCCAGCTCATCCACATCTTCATGTTTGGATTCATCTGCAATTAAACAAAGCAAACGTGTTTGTGCTGATGCGCAATTTATTGTTCCAAAAAGTGATAAAAATAAAAACTGTTGAATTATAGTGTGCAAAAATCTATAAATGATAGCGCTTCTGTCATTAAAAACTTAATACCGATGTTTAATAATACTAAAAGAAACATTCTGAAAGAATGCAATACTTTCTTAAAATATTGAAACAATTTCAATAAAGTGTCTAAACAAAGGAAAATAATATTTGAAAGGTTGAACTTACCAGTGAATGAGGTCTTGGAATTTTTTGAGGTCTTGATTGGAATTCTTGCTCTGTGGGTGTCGACTTCCCAGATTTTCTGCATTCAGAGTCGTGCGTCTTCTGGTTTTATACCTGTACTGCTCGTGCCATAAAGAGCAGAGCCCACGCGCA - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| npyct811/ct811 | Homozygous | ♀+/- ♂+/- | |||
| npyct811/ct811 | Homozygous | Unknown | Fig. 3  from Swaminathan et al., 2023 | ||
| npyct811/ct811 (AB/TL) | Homozygous | ♀+/- ♂+/- | 3 figures from Singh et al., 2017 | Fig. 7 from Singh et al., 2017 | |
| npyct811/+ | Heterozygous | Unknown | Fig. 3 from Swaminathan et al., 2023 | ||
| npyct811/+ (AB/TL) | Heterozygous | ♀+/- ♂+/- | 3 figures from Singh et al., 2017 | Fig. 7 from Singh et al., 2017 |
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Supplemental Information
- Genotyping protocol
- None
- Swaminathan, A., Gliksberg, M., Anbalagan, S., Wigoda, N., Levkowitz, G. (2023) Stress resilience is established during development and is regulated by complement factors. Cell Reports. 42:111973111973
- Singh, C., Rihel, J., Prober, D.A. (2017) Neuropeptide Y Regulates Sleep by Modulating Noradrenergic Signaling. Current biology : CB. 27(24):3796-3811.e5
- Chen, S., Oikonomou, G., Chiu, C.N., Niles, B.J., Liu, J., Lee, D.A., Antoshechkin, I., and Prober, D.A. (2013) A large-scale in vivo analysis reveals that TALENs are significantly more mutagenic than ZFNs generated using context-dependent assembly. Nucleic acids research. 41(4):2769-2778
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