Gene
npy
- ID
- ZDB-GENE-980526-438
- Name
- neuropeptide Y
- Symbol
- npy Nomenclature History
- Previous Names
-
- si:dkey-22m8.5
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Exhibits type 2 neuropeptide Y receptor binding activity. Involved in negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway; positive regulation of circadian sleep/wake cycle, sleep; and positive regulation of feeding behavior. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in several diseases, including Huntington's disease; alcohol use disorder; artery disease (multiple); epilepsy (multiple); and type 2 diabetes mellitus. Is expressed in several structures, including brain; digestive system; eye; immune system; and male organism. Orthologous to human NPY (neuropeptide Y).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 32 figures from 23 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Pancreatic hormone-like | Pancreatic hormone-like, conserved site |
|---|---|---|---|
|
UniProtKB:Q1LW93
|
96 | ||
|
UniProtKB:Q9I8P3
|
96 |
Interactions and Pathways
No data available
Plasmids
No data available