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Gene

npy

ID
ZDB-GENE-980526-438
Name
neuropeptide Y
Symbol
npy Nomenclature History
Previous Names
  • si:dkey-22m8.5
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Enables type 2 neuropeptide Y receptor binding activity. Acts upstream of or within negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway; positive regulation of circadian sleep/wake cycle, sleep; and positive regulation of feeding behavior. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including brain; digestive system; eye; immune system; and male organism. Human ortholog(s) of this gene implicated in several diseases, including Huntington's disease; alcohol use disorder; artery disease (multiple); epilepsy (multiple); and type 2 diabetes mellitus. Orthologous to human NPY (neuropeptide Y).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
27 figures from 19 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With npy Human Ortholog
No data available
Associated With npy Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020392 Pancreatic hormone-like, conserved site
Family IPR001955 Pancreatic hormone-like
Domain Details Per Protein
Protein Length Pancreatic hormone-like Pancreatic hormone-like, conserved site
UniProtKB:Q9I8P3 96
UniProtKB:Q1LW93 96
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations