| ZFIN ID: ZDB-EXP-250806-15 |
Experiment Conditions Description: chemical treatment by environment: carbetocin, chemical treatment by environment: cortisol
| chemical treatment by environment: carbetocin |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | carbetocin |
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| Synonyms: | 1-butanoic acid-2-(O-methyl-L-tyrosine)-1-carbaoxytocin, 1-butyric acid-2-(3-(p-methoxyphenyl)-L-alanine)oxytocin, 1-{[(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-9-(3-amino-3-oxopropyl)-12-[(2S)-butan-2-yl]-15-(4-methoxybenzyl)-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentaazacycloicosan-3-yl]carbonyl}-L-prolyl-L-leucylglycinamide, carbetocin, carbetocino, carbetocinum, deamino-2-O-methyltyrosine-1-carbaoxytocin |
| Definition: | Oxytocin in which the hydrogen on the phenolic hydroxy group is substituted by methyl, the amino group on the cysteine residue is substituted by hydrogen, and the sulfur of the cysteine residue is replaced by a methylene group. A synthetic carba-analogue of oxytocin, it is used to control bleeding after giving birth. Like oxytocin, it causes contraction of the uterus. |
| Ontology: | ChEBI [CHEBI:59204] ( EBI ) |
| chemical treatment by environment: cortisol |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | cortisol |
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| Synonyms: | (11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, 11beta,17,21-trihydroxypregn-4-ene-3,20-dione, 11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione, 11beta-hydrocortisone, 17-hydroxycorticosterone, 4-pregnen-11beta,17alpha,21-triol-3,20-dione, Cortisol, hidrocortisona, hydrocortisone, hydrocortisonum, Kendall's compound F, Reichstein's substance M |
| Definition: | A 17alpha-hydroxy-C21-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses. |
| Ontology: | ChEBI [CHEBI:17650] ( EBI ) |
| Publication: | Mairesse et al., 2018 |
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