cortisol

Term ID

CHEBI:17650

Synonyms

• (11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione
• 11beta,17,21-trihydroxypregn-4-ene-3,20-dione
• 11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione
• 11beta-hydrocortisone
• 17-hydroxycorticosterone
• 4-pregnen-11beta,17alpha,21-triol-3,20-dione
• cortisol
• hidrocortisona
• Hydrocortisone
• hydrocortisonum
• Kendall's compound F
• Reichstein's substance M

Definition

A 17α-hydroxy-C₂₁-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses.

References

• beilstein:1354819
• cas:50-23-7
• drugbank:DB00741
• drugcentral:1388
• kegg.compound:C00735
• kegg.drug:D00088
• lincs.smallmolecule:LSM-5980
• lipidmaps:LMST02030001
• patent:US2602769
• pdb-ccd:HCY
• pubmed:10438974
• pubmed:2268561
• wikipedia.en:Hydrocortisone

Ontology

ChEBI  ( EBI )

Resources

CTD