carbetocin

Term ID

CHEBI:59204

Synonyms

• 1-butanoic acid-2-(O-methyl-L-tyrosine)-1-carbaoxytocin
• 1-butyric acid-2-(3-(p-methoxyphenyl)-L-alanine)oxytocin
• 1-{[(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-9-(3-amino-3-oxopropyl)-12-[(2S)-butan-2-yl]-15-(4-methoxybenzyl)-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentaazacycloicosan-3-yl]carbonyl}-L-prolyl-L-leucylglycinamide
• carbetocin
• carbetocino
• carbetocinum
• deamino-2-O-methyltyrosine-1-carbaoxytocin

Definition

Oxytocin in which the hydrogen on the phenolic hydroxy group is substituted by methyl, the amino group on the cysteine residue is substituted by hydrogen, and the sulfur of the cysteine residue is replaced by a methylene group. A synthetic carba-analogue of oxytocin, it is used to control bleeding after giving birth. Like oxytocin, it causes contraction of the uterus.

References

• Beilstein:9985308
• CAS:37025-55-1
• DrugBank:DB01282
• Drug_Central:495
• KEGG:C18365
• KEGG:D07229
• Patent:DE2732175
• VSDB:1778

Ontology

ChEBI  ( EBI )

Resources

CTD