TALEN

TALEN1-rpgra

ID
ZDB-TALEN-240715-1
Name
TALEN1-rpgra
Previous Names
None
Target
Target Sequence 1
5' - AACAGAATCTCAATCATCAA - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Target Sequence 2
5' - GCATCTCCAGGCCTGGGCTT - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
zf4007 rpgra
Expression
Gene expression in Wild Types + TALEN1-rpgra
No data available
Phenotype
Phenotype resulting from TALEN1-rpgra
No data available
Phenotype of all Fish created by or utilizing TALEN1-rpgra
Phenotype Fish Conditions Figures
retinal pigmented epithelium lysosome Ab8-lamp1 labeling decreased distribution, abnormal rpgrazf4007/zf4007 standard conditions Figure 5. with image from Ren et al., 2025
retinal pigmented epithelium phagolysosome increased amount, abnormal rpgrazf4007/zf4007 standard conditions Figure 4. with image from Ren et al., 2025
retinal pigmented epithelium lysosome morphology, abnormal rpgrazf4007/zf4007 standard conditions Figure 4. with image from Ren et al., 2025
retinal pigmented epithelium cell-cell junction structurally discontinuous, abnormal rpgrazf4007/zf4007 standard conditions Figure 1. with image from Ren et al., 2025
retinal pigmented epithelium Ab2-rab7 labeling decreased amount, abnormal rpgrazf4007/zf4007 standard conditions Figure 4. with image from Ren et al., 2025
retinal pigmented epithelium nucleus morphology, abnormal rpgrazf4007/zf4007 standard conditions Figure 1. with image from Ren et al., 2025
retinal pigmented epithelium triglyceride increased amount, abnormal rpgrazf4007/zf4007 standard conditions Figure 2. with image from Ren et al., 2025
retinal outer nuclear layer decreased thickness, abnormal rpgrazf4007/zf4007 standard conditions Figure 1. with image from Ren et al., 2025
retinal pigmented epithelium lipid droplet increased diameter, abnormal rpgrazf4007/zf4007 standard conditions Figure 2. with image from Ren et al., 2025
retinal pigmented epithelium Ab2-lamp2 labeling decreased amount, abnormal rpgrazf4007/zf4007 standard conditions Figure 4. with image from Ren et al., 2025
retinal pigmented epithelium Ab8-lamp1 labeling decreased amount, abnormal rpgrazf4007/zf4007 standard conditions Figure 4. with image from Ren et al., 2025
retinal pigmented epithelium lipid droplet increased amount, abnormal rpgrazf4007/zf4007 standard conditions Figure 2. with image,  Figure 4. with image from Ren et al., 2025
retinal pigmented epithelium cell shape, abnormal rpgrazf4007/zf4007 standard conditions Figure 1. with image from Ren et al., 2025
retinal pigmented epithelium Ab1-rpgra labeling absent, abnormal rpgrazf4007/zf4007 standard conditions Figure 1. with image from Ren et al., 2025
retinal pigmented epithelium lysosome organization decreased process quality, abnormal rpgrazf4007/zf4007 standard conditions Figure 4. with image,  Figure 5. with image from Ren et al., 2025
retinal pigmented epithelium regulation of lysosomal lumen pH decreased process quality, abnormal rpgrazf4007/zf4007 standard conditions Figure 5. with image from Ren et al., 2025
retina photoreceptor outer segment decreased length, abnormal rpgrazf4007/zf4007 standard conditions Figure 1. with image from Ren et al., 2025
retinal pigmented epithelium Ab3-ctsb labeling decreased amount, abnormal rpgrazf4007/zf4007 standard conditions Figure 4. with image from Ren et al., 2025
Citations
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