TALEN

TALEN1-cerkl

ID

ZDB-TALEN-170720-1

Name

TALEN1-cerkl

Previous Names

None

Target

cerkl (1)

Target Sequence 1

5' - AAATCGATAAGTGTCC - 3'

Target Sequence 2

5' - CGCGCAACTCTTCCTGAC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
hzu3	cerkl

Expression

Gene expression in Wild Types + TALEN1-cerkl

No data available

Phenotype

Phenotype resulting from TALEN1-cerkl

No data available

Phenotype of all Fish created by or utilizing TALEN1-cerkl

Phenotype	Fish	Conditions	Figures
retinal outer nuclear layer ab5-rho labeling spatial pattern, abnormal	cerkl^hzu3/hzu3	standard conditions	Figure 5. from Gao et al., 2026
retinal outer nuclear layer ab5-rho labeling spatial pattern, ameliorated	cerkl^hzu3/hzu3	chemical treatment by environment: phosphatidylcholine	Figure 5. from Gao et al., 2026
retinal pigmented epithelium bile acid biosynthetic process increased occurrence, abnormal	cerkl^hzu3/hzu3	standard conditions	Figure 2. from Gao et al., 2026
eye Ab1-mertk labeling decreased amount, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. 7 from Yu et al., 2017
retinal pigmented epithelium arachidonate metabolic process increased occurrence, abnormal	cerkl^hzu3/hzu3	standard conditions	Figure 2. from Gao et al., 2026
retinal photoreceptor layer has extra parts of type retinal photoreceptor layer vesicle, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. S4 from Yu et al., 2017
retinal inner nuclear layer apoptotic process increased occurrence, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. 4 from Yu et al., 2017
photoreceptor outer segment layer decreased thickness, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. 3 from Yu et al., 2017
retinal pigmented epithelium Ab8-tjp1 labeling spatial pattern, abnormal	cerkl^hzu3/hzu3	standard conditions	Figure 1. from Gao et al., 2026
eye lamp1b expression decreased amount, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. S5 from Yu et al., 2017
retina regulation of apoptotic cell clearance process quality, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. S4 from Yu et al., 2017
retinal pigmented epithelium lipid metabolic process increased occurrence, abnormal	cerkl^hzu3/hzu3	standard conditions	Figure 2. from Gao et al., 2026
retinal rod cell photoreceptor outer segment disorganized, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. 5 from Yu et al., 2017
eye mertka expression decreased amount, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. 7, Fig. S5 from Yu et al., 2017
retinal pigmented epithelium lipid droplet formation increased occurrence, ameliorated	cerkl^hzu3/hzu3	chemical treatment by environment: phosphatidylcholine	Figure 5. from Gao et al., 2026
eye ctsd expression decreased amount, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. S5 from Yu et al., 2017
retinal rod cell photoreceptor outer segment degenerate, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. 5, Fig. 7 from Yu et al., 2017
retinal pigmented epithelium linoleic acid metabolic process increased occurrence, abnormal	cerkl^hzu3/hzu3	standard conditions	Figure 2. from Gao et al., 2026
eye ab1-gnat1 labeling decreased amount, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. 6 from Yu et al., 2017
detection of light stimulus involved in visual perception decreased process quality, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. 2 from Yu et al., 2017
retinal cone cell photoreceptor outer segment degenerate, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. 5 from Yu et al., 2017
retina CDP-choline pathway increased occurrence, abnormal	cerkl^hzu3/hzu3	standard conditions	Figure 6. from Gao et al., 2026
retinal pigmented epithelium steroid hormone biosynthetic process increased occurrence, abnormal	cerkl^hzu3/hzu3	standard conditions	Figure 2. from Gao et al., 2026
retinal pigmented epithelium glycerophospholipid metabolic process increased occurrence, abnormal	cerkl^hzu3/hzu3	standard conditions	Figure 2. from Gao et al., 2026
retinal cone cell decreased amount, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. 3, Fig. 5 from Yu et al., 2017
retinal outer nuclear layer ab5-rho labeling amount, ameliorated	cerkl^hzu3/hzu3	chemical treatment by environment: phosphatidylcholine	Figure 5. from Gao et al., 2026
photoreceptor cell photoreceptor outer segment degenerate, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. 3 from Yu et al., 2017
photoreceptor cell photoreceptor outer segment disorganized, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. 3 from Yu et al., 2017
retinal pigmented epithelium ether lipid metabolic process increased occurrence, abnormal	cerkl^hzu3/hzu3	standard conditions	Figure 2. from Gao et al., 2026
retinal pigmented epithelium triglyceride increased amount, abnormal	cerkl^hzu3/hzu3	standard conditions	Figure 2. , Figure 5. from Gao et al., 2026
eye photoreceptor cell photoreceptor outer segment detached from eye photoreceptor cell photoreceptor inner segment, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. S4 from Yu et al., 2017
retinal outer nuclear layer ab5-rho labeling decreased amount, abnormal	cerkl^hzu3/hzu3	standard conditions	Figure 5. from Gao et al., 2026
eye ab1-grk1 labeling decreased amount, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. 6 from Yu et al., 2017
retinal photoreceptor layer apoptotic process increased occurrence, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. 4 from Yu et al., 2017
eye rho expression increased amount, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. S3 from Yu et al., 2017
retinal rod cell photoreceptor outer segment decreased length, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. 5 from Yu et al., 2017
eye ab5-rho labeling decreased amount, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. 6 from Yu et al., 2017
retinal rod cell decreased amount, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. 3, Fig. 5 from Yu et al., 2017
retinal outer nuclear layer decreased thickness, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. 3 from Yu et al., 2017
eye ab1-gnb1 labeling decreased amount, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. 6 from Yu et al., 2017
retinal cone cell photoreceptor outer segment decreased length, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. 5 from Yu et al., 2017
retinal rod cell photoreceptor disc membrane disorganized, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. 7 from Yu et al., 2017
photoreceptor cell photoreceptor outer segment decreased length, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. 3 from Yu et al., 2017
retinal pigmented epithelium lipid droplet formation increased occurrence, abnormal	cerkl^hzu3/hzu3	standard conditions	Figure 1. , Figure 5. from Gao et al., 2026
retinal pigmented epithelium triglyceride increased amount, ameliorated	cerkl^hzu3/hzu3	chemical treatment by environment: phosphatidylcholine	Figure 5. from Gao et al., 2026
eye gnb1b expression increased amount, abnormal	cerkl^hzu3/hzu3	standard conditions	Fig. S3 from Yu et al., 2017

Citations