Morpholino

MO1-myo5b

ID

ZDB-MRPHLNO-141231-1

Name

MO1-myo5b

Previous Names

None

Target

myo5b (1)

Sequence

5' - GATCTTCTATTACTGACCGAGTTGA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

Splice-blocking MO.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-myo5b

Expressed Gene	Anatomy	Figures
cdh1	epidermal cell epidermis	Fig 3 , Fig 7 from Phatak et al., 2021
cldn7b	epidermis	Fig 3 from Phatak et al., 2021
cldne	epidermis	Fig 3 from Phatak et al., 2021
dsc2l	epidermis	Fig 3 from Phatak et al., 2021
grhl3	epidermis	Fig 3 from Phatak et al., 2021
lamp1b	peridermal cell lysosome	Fig. 2 from Sonal et al., 2014
llgl2	peridermal cell membrane	Fig. 5 from Sonal et al., 2014
oclna	epidermis	Fig 3 from Phatak et al., 2021

Phenotype

Phenotype resulting from MO1-myo5b

Phenotype	Fish	Figures
cell endosome increased accumulation periderm, abnormal	zf106Tg + MO1-myo5b	Fig. 2 from Sonal et al., 2014
cell lysosome increased accumulation periderm, abnormal	zf106Tg + MO1-myo5b	Fig. 2 from Sonal et al., 2014
cell vesicle increased accumulation periderm, abnormal	zf106Tg + MO1-myo5b	Fig. 2 from Sonal et al., 2014
epidermal basal stratum cell population proliferation increased occurrence, abnormal	WT + MO1-myo5b	Fig. 5 from Sonal et al., 2014
epidermal cell ab2-cdh1 labeling increased amount, abnormal	zf106Tg/zf106Tg + MO1-myo5b	Fig 7 from Phatak et al., 2021
epidermal cell ab1-llgl2 labeling increased amount, abnormal	zf106Tg/zf106Tg + MO1-myo5b	Fig 6 from Phatak et al., 2021
epidermal cell cdh1 expression increased amount, abnormal	zf106Tg/zf106Tg + MO1-myo5b	Fig 7 from Phatak et al., 2021
epidermal cell increased thickness, abnormal	zf106Tg/zf106Tg + MO1-myo5b	Fig 6 from Phatak et al., 2021
epidermal cell irregular spatial pattern, abnormal	zf106Tg/zf106Tg + MO1-myo5b	Fig 6 from Phatak et al., 2021
epidermal cell ab2-cdh1 labeling spatial pattern, abnormal	zf106Tg/zf106Tg + MO1-myo5b	Fig 7 from Phatak et al., 2021
epidermal cell cdh1 expression spatial pattern, abnormal	zf106Tg/zf106Tg + MO1-myo5b	Fig 7 from Phatak et al., 2021
epidermal cell ab1-llgl2 labeling spatial pattern, abnormal	zf106Tg/zf106Tg + MO1-myo5b	Fig 6 from Phatak et al., 2021
epidermal cell delamination cellular spatiotemporal quality, abnormal	zf106Tg/zf106Tg + MO1-myo5b	Fig 7 from Phatak et al., 2021
epidermal cell delamination increased frequency, abnormal	TU + MO1-myo5b	Fig 4 , Fig 5 from Phatak et al., 2021
epidermal cell membrane ab1-llgl2 labeling spatial pattern, abnormal	zf106Tg/zf106Tg + MO1-myo5b	Fig 6 from Phatak et al., 2021
epidermis dsc2l expression increased amount, abnormal	TU + MO1-myo5b	Fig 3 from Phatak et al., 2021
epidermis cldne expression increased amount, abnormal	TU + MO1-myo5b	Fig 3 from Phatak et al., 2021
epidermis cldn7b expression increased amount, abnormal	TU + MO1-myo5b	Fig 3 from Phatak et al., 2021
epidermis oclna expression increased amount, abnormal	TU + MO1-myo5b	Fig 3 from Phatak et al., 2021
epidermis cdh1 expression increased amount, abnormal	TU + MO1-myo5b	Fig 3 from Phatak et al., 2021
epidermis grhl3 expression increased amount, abnormal	TU + MO1-myo5b	Fig 3 from Phatak et al., 2021
periderm cell population proliferation increased occurrence, abnormal	WT + MO1-myo5b	Fig. 5 from Sonal et al., 2014
peridermal cell decreased size, abnormal	zf106Tg + MO1-myo5b	Fig. 4 , Fig. 5 from Sonal et al., 2014
peridermal cell increased amount, abnormal	WT + MO1-myo5b	Fig. 5 from Sonal et al., 2014
peridermal cell apical plasma membrane decreased area, abnormal	zf106Tg + MO1-myo5b	Fig. 4 from Sonal et al., 2014
peridermal cell basolateral plasma membrane decreased area, abnormal	zf106Tg + MO1-myo5b	Fig. 4 from Sonal et al., 2014
peridermal cell cell projection membrane absent, abnormal	zf106Tg + MO1-myo5b	Fig. 4 from Sonal et al., 2014
peridermal cell delamination increased frequency, abnormal	zf106Tg/zf106Tg + MO1-myo5b	Fig 1 from Phatak et al., 2021
peridermal cell epithelial structure maintenance decreased process quality, abnormal	zf106Tg/zf106Tg + MO1-myo5b	Fig 1 from Phatak et al., 2021
peridermal cell organelle membrane EGFP expression spatial pattern, abnormal	zf106Tg/zf106Tg + MO1-myo5b	Fig 1 , Fig 4 from Phatak et al., 2021
peridermal cell plasma membrane EGFP expression spatial pattern, abnormal	zf106Tg/zf106Tg + MO1-myo5b	Fig 1 , Fig 4 from Phatak et al., 2021
peridermal cell regulation of cell adhesion process quality, abnormal	zf106Tg/zf106Tg + MO1-myo5b	Fig 1 from Phatak et al., 2021

Phenotype of all Fish created by or utilizing MO1-myo5b

Phenotype	Fish	Conditions	Figures
epidermal cell membrane ab1-llgl2 labeling spatial pattern, abnormal	zf106Tg/zf106Tg + MO1-myo5b	standard conditions	Fig 6 from Phatak et al., 2021
epidermal cell irregular spatial pattern, abnormal	zf106Tg/zf106Tg + MO1-myo5b	standard conditions	Fig 6 from Phatak et al., 2021
epidermal cell cdh1 expression increased amount, abnormal	zf106Tg/zf106Tg + MO1-myo5b	standard conditions	Fig 7 from Phatak et al., 2021
epidermal cell cdh1 expression spatial pattern, abnormal	zf106Tg/zf106Tg + MO1-myo5b	standard conditions	Fig 7 from Phatak et al., 2021
peridermal cell organelle membrane EGFP expression spatial pattern, abnormal	zf106Tg/zf106Tg + MO1-myo5b	standard conditions	Fig 1 , Fig 4 from Phatak et al., 2021
epidermal cell ab2-cdh1 labeling spatial pattern, abnormal	zf106Tg/zf106Tg + MO1-myo5b	standard conditions	Fig 7 from Phatak et al., 2021
peridermal cell regulation of cell adhesion process quality, abnormal	zf106Tg/zf106Tg + MO1-myo5b	standard conditions	Fig 1 from Phatak et al., 2021
epidermal cell ab1-llgl2 labeling spatial pattern, abnormal	zf106Tg/zf106Tg + MO1-myo5b	standard conditions	Fig 6 from Phatak et al., 2021
peridermal cell delamination increased frequency, abnormal	zf106Tg/zf106Tg + MO1-myo5b	standard conditions	Fig 1 from Phatak et al., 2021
epidermal cell ab1-llgl2 labeling increased amount, abnormal	zf106Tg/zf106Tg + MO1-myo5b	standard conditions	Fig 6 from Phatak et al., 2021
epidermal cell delamination cellular spatiotemporal quality, abnormal	zf106Tg/zf106Tg + MO1-myo5b	standard conditions	Fig 7 from Phatak et al., 2021
epidermal cell ab2-cdh1 labeling increased amount, abnormal	zf106Tg/zf106Tg + MO1-myo5b	standard conditions	Fig 7 from Phatak et al., 2021
peridermal cell epithelial structure maintenance decreased process quality, abnormal	zf106Tg/zf106Tg + MO1-myo5b	standard conditions	Fig 1 from Phatak et al., 2021
epidermal cell increased thickness, abnormal	zf106Tg/zf106Tg + MO1-myo5b	standard conditions	Fig 6 from Phatak et al., 2021
peridermal cell plasma membrane EGFP expression spatial pattern, abnormal	zf106Tg/zf106Tg + MO1-myo5b	standard conditions	Fig 1 , Fig 4 from Phatak et al., 2021
epidermis cdh1 expression increased amount, abnormal	TU + MO1-myo5b	standard conditions	Fig 3 from Phatak et al., 2021
epidermal cell delamination increased frequency, abnormal	TU + MO1-myo5b	standard conditions	Fig 4 , Fig 5 from Phatak et al., 2021
epidermis cldne expression increased amount, abnormal	TU + MO1-myo5b	standard conditions	Fig 3 from Phatak et al., 2021
epidermis cldn7b expression increased amount, abnormal	TU + MO1-myo5b	standard conditions	Fig 3 from Phatak et al., 2021
epidermis grhl3 expression increased amount, abnormal	TU + MO1-myo5b	standard conditions	Fig 3 from Phatak et al., 2021
epidermis oclna expression increased amount, abnormal	TU + MO1-myo5b	standard conditions	Fig 3 from Phatak et al., 2021
epidermis dsc2l expression increased amount, abnormal	TU + MO1-myo5b	standard conditions	Fig 3 from Phatak et al., 2021
periderm cell population proliferation increased occurrence, abnormal	WT + MO1-myo5b	standard conditions	Fig. 5 from Sonal et al., 2014
epidermal basal stratum cell population proliferation increased occurrence, abnormal	WT + MO1-myo5b	standard conditions	Fig. 5 from Sonal et al., 2014
peridermal cell increased amount, abnormal	WT + MO1-myo5b	standard conditions	Fig. 5 from Sonal et al., 2014
cell lysosome increased accumulation periderm, abnormal	zf106Tg + MO1-myo5b	standard conditions	Fig. 2 from Sonal et al., 2014
peridermal cell apical plasma membrane decreased area, abnormal	zf106Tg + MO1-myo5b	standard conditions	Fig. 4 from Sonal et al., 2014
peridermal cell decreased size, abnormal	zf106Tg + MO1-myo5b	standard conditions	Fig. 4 , Fig. 5 from Sonal et al., 2014
cell vesicle increased accumulation periderm, abnormal	zf106Tg + MO1-myo5b	standard conditions	Fig. 2 from Sonal et al., 2014
peridermal cell cell projection membrane absent, abnormal	zf106Tg + MO1-myo5b	standard conditions	Fig. 4 from Sonal et al., 2014
cell endosome increased accumulation periderm, abnormal	zf106Tg + MO1-myo5b	standard conditions	Fig. 2 from Sonal et al., 2014
peridermal cell basolateral plasma membrane decreased area, abnormal	zf106Tg + MO1-myo5b	standard conditions	Fig. 4 from Sonal et al., 2014
epidermal cell delamination normal frequency, ameliorated	grhl3^{zf3707/zf3707} + MO1-myo5b	standard conditions	Fig 4 from Phatak et al., 2021
epidermal cell delamination cellular spatiotemporal quality, abnormal	zf106Tg/zf106Tg + MO1-myo5b + MO4-grhl3	standard conditions	Fig 7 from Phatak et al., 2021
peridermal cell organelle membrane EGFP expression spatial pattern, ameliorated	zf106Tg/zf106Tg + MO1-myo5b + MO4-grhl3	standard conditions	Fig 4 from Phatak et al., 2021
epidermal cell membrane ab1-llgl2 labeling spatial pattern, abnormal	zf106Tg/zf106Tg + MO1-myo5b + MO4-grhl3	standard conditions	Fig 6 from Phatak et al., 2021
epidermal cell decreased thickness, abnormal	zf106Tg/zf106Tg + MO1-myo5b + MO4-grhl3	standard conditions	Fig 6 from Phatak et al., 2021
epidermal cell ab1-llgl2 labeling spatial pattern, abnormal	zf106Tg/zf106Tg + MO1-myo5b + MO4-grhl3	standard conditions	Fig 6 from Phatak et al., 2021
epidermal cell ab2-cdh1 labeling spatial pattern, ameliorated	zf106Tg/zf106Tg + MO1-myo5b + MO4-grhl3	standard conditions	Fig 7 from Phatak et al., 2021
epidermal cell ab1-llgl2 labeling increased amount, abnormal	zf106Tg/zf106Tg + MO1-myo5b + MO4-grhl3	standard conditions	Fig 6 from Phatak et al., 2021
epidermal cell cell division increased frequency, abnormal	zf106Tg/zf106Tg + MO1-myo5b + MO4-grhl3	standard conditions	Fig 6 from Phatak et al., 2021
peridermal cell plasma membrane EGFP expression spatial pattern, ameliorated	zf106Tg/zf106Tg + MO1-myo5b + MO4-grhl3	standard conditions	Fig 4 from Phatak et al., 2021
epidermal cell irregular spatial pattern, exacerbated	zf106Tg/zf106Tg + MO1-myo5b + MO4-grhl3	standard conditions	Fig 6 from Phatak et al., 2021
epidermal cell ab2-cdh1 labeling amount, ameliorated	zf106Tg/zf106Tg + MO1-myo5b + MO4-grhl3	standard conditions	Fig 7 from Phatak et al., 2021
epidermal cell cdh1 expression amount, ameliorated	zf106Tg/zf106Tg + MO1-myo5b + MO4-grhl3	standard conditions	Fig 7 from Phatak et al., 2021
epidermal cell cdh1 expression spatial pattern, ameliorated	zf106Tg/zf106Tg + MO1-myo5b + MO4-grhl3	standard conditions	Fig 7 from Phatak et al., 2021
epidermal cell delamination normal frequency, ameliorated	TU + MO1-myo5b + MO4-grhl3	standard conditions	Fig 4 from Phatak et al., 2021
epidermal cell delamination increased frequency, exacerbated	TU + MO1-myo5b + MO4-grhl3	standard conditions	Fig 5 from Phatak et al., 2021
periderm cell decreased amount, abnormal	WT + MO1-myo5b + MO2-tp63	standard conditions	Fig. 5 from Sonal et al., 2014
peridermal cell apoptotic process increased occurrence, abnormal	WT + MO1-myo5b + MO2-tp63	standard conditions	Fig. 5 from Sonal et al., 2014

Citations