Morpholino

MO1-gata3

ID

ZDB-MRPHLNO-100811-4

Name

MO1-gata3

Previous Names

None

Target

gata3 (1)

Sequence

5' - CCGGACTTACTTCCATCGTTTATTT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

Translation-blocking MO.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-gata3

Expressed Gene	Anatomy	Figures
bmp2b	whole organism	Fig. 7 from Yao et al., 2014
cxcr4b	olfactory placode	Fig. 4 from Yao et al., 2014
fgfr1a	whole organism	Fig. 7 from Yao et al., 2014
fgfr2	whole organism	Fig. 7 from Yao et al., 2014
fgfr3	whole organism	Fig. 7 from Yao et al., 2014
fgfr4	whole organism	Fig. 7 from Yao et al., 2014
foxe3	solid lens vesicle	Fig. 4 from Yao et al., 2014
gad1b	lateral floor plate Kolmer-Agduhr neuron (not) spinal cord Kolmer-Agduhr neuron VeLD	Fig. 9 from Yang et al., 2010
pax2a	otic placode	Fig. 4 from Yao et al., 2014
six4b	neurogenic field	Fig. 4 from Yao et al., 2014
sox3	epibranchial field	Fig. 4 from Yao et al., 2014
tal2	lateral floor plate Kolmer-Agduhr neuron (not) spinal cord Kolmer-Agduhr neuron VeLD	Fig. 9 from Yang et al., 2010

Phenotype

Phenotype resulting from MO1-gata3

Phenotype	Fish	Figures
embryonic neurocranium morphogenesis decreased process quality, abnormal	WT + MO1-gata3	Fig. 4 , Fig. S1 from Sheehan-Rooney et al., 2013
epibranchial field sox3 expression decreased distribution, abnormal	TU + MO1-gata3	Fig. 4 from Yao et al., 2014
neurocranial trabecula malformed, abnormal	AB + MO1-gata3	Fig. 4 from Sheehan-Rooney et al., 2013
neurocranial trabecula chondrocyte disorganized, abnormal	AB + MO1-gata3	Fig. 4 from Sheehan-Rooney et al., 2013
neurocranium lacks all parts of type neurocranial trabecula, abnormal	WT + MO1-gata3	Fig. 4 , Fig. S1 from Sheehan-Rooney et al., 2013
neurogenic field six4b expression decreased amount, abnormal	TU + MO1-gata3	Fig. 4 from Yao et al., 2014
olfactory placode cxcr4b expression decreased distribution, abnormal	TU + MO1-gata3	Fig. 4 from Yao et al., 2014
otic placode pax2a expression decreased amount, abnormal	TU + MO1-gata3	Fig. 4 from Yao et al., 2014
solid lens vesicle foxe3 expression decreased distribution, abnormal	TU + MO1-gata3	Fig. 4 from Yao et al., 2014
spinal cord Kolmer-Agduhr neuron undifferentiated, abnormal	WT + MO1-gata3	Fig. 9 from Yang et al., 2010
ventral spinal cord interneuron differentiation disrupted, abnormal	WT + MO1-gata3	Fig. 9 from Yang et al., 2010
whole organism fgfr3 expression decreased amount, abnormal	TU + MO1-gata3	Fig. 7 from Yao et al., 2014
whole organism fgfr4 expression decreased amount, abnormal	TU + MO1-gata3	Fig. 7 from Yao et al., 2014
whole organism fgfr2 expression decreased amount, abnormal	TU + MO1-gata3	Fig. 7 from Yao et al., 2014
whole organism fgfr1a expression decreased amount, abnormal	TU + MO1-gata3	Fig. 7 from Yao et al., 2014
whole organism bmp2b expression increased amount, abnormal	TU + MO1-gata3	Fig. 7 from Yao et al., 2014

Phenotype of all Fish created by or utilizing MO1-gata3

Phenotype	Fish	Conditions	Figures
embryonic neurocranium morphogenesis decreased process quality, abnormal	AB + MO1-gata3	standard conditions	Fig. 4 from Sheehan-Rooney et al., 2013
neurocranium lacks all parts of type neurocranial trabecula, abnormal	AB + MO1-gata3	standard conditions	Fig. 4 from Sheehan-Rooney et al., 2013
neurocranial trabecula chondrocyte disorganized, abnormal	AB + MO1-gata3	standard conditions	Fig. 4 from Sheehan-Rooney et al., 2013
neurocranial trabecula malformed, abnormal	AB + MO1-gata3	standard conditions	Fig. 4 from Sheehan-Rooney et al., 2013
whole organism fgfr1a expression decreased amount, abnormal	TU + MO1-gata3	control	Fig. 7 from Yao et al., 2014
epibranchial field sox3 expression decreased distribution, abnormal	TU + MO1-gata3	control	Fig. 4 from Yao et al., 2014
neurogenic field six4b expression decreased amount, abnormal	TU + MO1-gata3	control	Fig. 4 from Yao et al., 2014
whole organism bmp2b expression increased amount, abnormal	TU + MO1-gata3	control	Fig. 7 from Yao et al., 2014
whole organism fgfr3 expression decreased amount, abnormal	TU + MO1-gata3	control	Fig. 7 from Yao et al., 2014
solid lens vesicle pitx3 expression spatial pattern, ameliorated	TU + MO1-gata3	chemical treatment: XAV939	Fig. 5 from Yao et al., 2014
solid lens vesicle foxe3 expression decreased distribution, abnormal	TU + MO1-gata3	control	Fig. 4 from Yao et al., 2014
olfactory placode cxcr4b expression decreased distribution, abnormal	TU + MO1-gata3	control	Fig. 4 from Yao et al., 2014
otic placode pax2a expression decreased amount, abnormal	TU + MO1-gata3	control	Fig. 4 from Yao et al., 2014
whole organism fgfr4 expression decreased amount, abnormal	TU + MO1-gata3	control	Fig. 7 from Yao et al., 2014
olfactory placode cxcr4b expression spatial pattern, ameliorated	TU + MO1-gata3	chemical treatment: XAV939	Fig. 5 from Yao et al., 2014
whole organism fgfr2 expression decreased amount, abnormal	TU + MO1-gata3	control	Fig. 7 from Yao et al., 2014
neurocranium lacks all parts of type neurocranial trabecula, abnormal	WT + MO1-gata3	standard conditions	Fig. S1 from Sheehan-Rooney et al., 2013
embryonic neurocranium morphogenesis decreased process quality, abnormal	WT + MO1-gata3	standard conditions	Fig. S1 from Sheehan-Rooney et al., 2013
spinal cord Kolmer-Agduhr neuron undifferentiated, abnormal	WT + MO1-gata3	standard conditions	Fig. 9 from Yang et al., 2010
ventral spinal cord interneuron differentiation disrupted, abnormal	WT + MO1-gata3	standard conditions	Fig. 9 from Yang et al., 2010
spinal cord sox1a expression decreased distribution, abnormal	ABO + MO1-gata2a + MO1-gata3	standard conditions	Fig. 5 from Gerber et al., 2019
spinal cord sox1b expression decreased distribution, abnormal	ABO + MO1-gata2a + MO1-gata3	standard conditions	Fig. 5 from Gerber et al., 2019
spinal cord gad1b expression decreased distribution, abnormal	ABO + MO1-gata2a + MO1-gata3	standard conditions	Fig. 5 from Gerber et al., 2019

Citations