Morpholino

MO1-sox3

ID

ZDB-MRPHLNO-081113-1

Name

MO1-sox3

Previous Names

None

Target

sox3 (1)

Sequence

5' - GGTGCCAAGCACTCGAAAGAAAACG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Genome Build: GRCz11Chromosome: 14

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-sox3

No data available

Phenotype

Phenotype resulting from MO1-sox3

No data available

Phenotype of all Fish created by or utilizing MO1-sox3

Phenotype	Fish	Conditions	Figures
eye decreased size, abnormal	WT + MO1-sox3 + MO2-sox3	standard conditions	Fig. 6 from Dee et al., 2008
central nervous system development disrupted, abnormal	WT + MO1-sox3 + MO2-sox3	standard conditions	Fig. 5 , Fig. 6 , Fig. 7 from Dee et al., 2008
otic vesicle aplastic, abnormal	WT + MO1-sox3 + MO2-sox3	standard conditions	Fig. 9 from Dee et al., 2008
brain morphology, abnormal	WT + MO1-sox3 + MO2-sox3	standard conditions	Fig. 6 from Dee et al., 2008
otic vesicle decreased size, abnormal	WT + MO1-sox3 + MO2-sox3	standard conditions	Fig. 9 from Dee et al., 2008
central nervous system apoptotic, abnormal	WT + MO1-sox3 + MO2-sox3	standard conditions	Fig. 6 from Dee et al., 2008
brain nucleus decreased amount, abnormal	WT + MO1-sox3 + MO2-sox3	standard conditions	Fig. 6 from Dee et al., 2008
brain apoptotic, abnormal	WT + MO1-sox3 + MO2-sox3	standard conditions	Fig. 6 from Dee et al., 2008
central canal unlumenized, abnormal	WT + MO1-sox3 + MO2-sox3	standard conditions	Fig. 6 from Dee et al., 2008
brain decreased size, abnormal	WT + MO1-sox3 + MO2-sox3	standard conditions	Fig. 6 from Dee et al., 2008
roof plate rhombomere region left-right axis decreased width, abnormal	WT + MO1-sox3 + MO2-sox3	standard conditions	Fig. 6 from Dee et al., 2008
spinal cord nucleus decreased amount, abnormal	WT + MO1-sox3 + MO2-sox3	standard conditions	Fig. 6 from Dee et al., 2008
neuron differentiation disrupted, abnormal	WT + MO1-sox3 + MO2-sox3	standard conditions	Fig. 8 , Fig. 9 from Dee et al., 2008
whole organism decreased length, abnormal	WT + MO1-sox3 + MO2-sox3	standard conditions	Fig. 6 , Fig. 7 from Dee et al., 2008
otic vesicle morphology, abnormal	WT + MO1-sox3 + MO2-sox3	standard conditions	Fig. 9 from Dee et al., 2008
neurogenic placode morphology, abnormal	WT + MO1-sox3 + MO2-sox3	standard conditions	Fig. 9 from Dee et al., 2008

Citations

Include unpublished citations

Dee, C.T., Hirst, C.S., Shih, Y.H., Tripathi, V.B., Patient, R.K., and Scotting, P.J. (2008) Sox3 regulates both neural fate and differentiation in the zebrafish ectoderm. Developmental Biology. 320(1):289-301

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