Morpholino

MO1-klf6a

ID

ZDB-MRPHLNO-080208-5

Name

MO1-klf6a

Previous Names

KLF6a-atg (1)
MO1-copeb

Target

klf6a (1)

Sequence

5' - CACATTGGTAGAACATCCATTGCAA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

This morpholino targets the transcription start site.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-klf6a

Expressed Gene	Anatomy	Figures
ccl25b	intermediate cell mass of mesoderm posterior region whole organism posterior region	Fig. 5 from Xue et al., 2017
gata1a	erythroid lineage cell	Fig. 5 from Xue et al., 2015
hbbe1.1	erythroid lineage cell nucleate erythrocyte	Fig. 5 from Xue et al., 2015
hbbe3	nucleate erythrocyte	Fig. 5 from Xue et al., 2015
myb	hematopoietic stem cell	Fig. 3 from Xue et al., 2017

Phenotype

Phenotype resulting from MO1-klf6a

Phenotype	Fish	Figures
blood island cell cycle process quality, abnormal	sd2Tg + MO1-klf6a	Fig. 6 from Xue et al., 2015
blood island cell population proliferation decreased process quality, abnormal	sd2Tg + MO1-klf6a	Fig. 6 from Xue et al., 2015
caudal hematopoietic tissue hematopoietic multipotent progenitor cell decreased amount, abnormal	la2Tg + MO1-klf6a	Fig. 3 from Xue et al., 2017
caudal hematopoietic tissue hematopoietic stem cell decreased amount, abnormal	ioz1Tg; s896Tg + MO1-klf6a	Fig. 3 from Xue et al., 2017
caudal hematopoietic tissue hematopoietic stem cell proliferation decreased occurrence, abnormal	TU + MO1-klf6a	Fig. 3 from Xue et al., 2017
caudal vein plexus blood vessel endothelial cell migration decreased process quality, abnormal	ci5Tg; y7Tg + MO1-klf6a	Fig 4 from Wen et al., 2021
erythrocyte maturation arrested, abnormal	WT + MO1-klf6a	Fig. 5 from Xue et al., 2015
intermediate cell mass of mesoderm posterior region ccl25b expression decreased amount, abnormal	TU + MO1-klf6a	Fig. 5 from Xue et al., 2017
nucleate erythrocyte decreased amount, abnormal	WT + MO1-klf6a	Fig. 5 , Fig. 6 from Xue et al., 2015
primitive erythrocyte differentiation arrested, abnormal	WT + MO1-klf6a	Fig. 5 from Xue et al., 2015
whole organism posterior region ccl25b expression decreased amount, abnormal	TU + MO1-klf6a	Fig. 5 from Xue et al., 2017

Phenotype of all Fish created by or utilizing MO1-klf6a

Phenotype	Fish	Conditions	Figures
intermediate cell mass of mesoderm posterior region ccl25b expression decreased amount, abnormal	TU + MO1-klf6a	standard conditions	Fig. 5 from Xue et al., 2017
whole organism posterior region ccl25b expression decreased amount, abnormal	TU + MO1-klf6a	standard conditions	Fig. 5 from Xue et al., 2017
caudal hematopoietic tissue hematopoietic stem cell proliferation decreased occurrence, abnormal	TU + MO1-klf6a	standard conditions	Fig. 3 from Xue et al., 2017
erythrocyte maturation arrested, abnormal	WT + MO1-klf6a	standard conditions	Fig. 5 from Xue et al., 2015
nucleate erythrocyte decreased amount, abnormal	WT + MO1-klf6a	standard conditions	Fig. 5 , Fig. 6 from Xue et al., 2015
primitive erythrocyte differentiation arrested, abnormal	WT + MO1-klf6a	standard conditions	Fig. 5 from Xue et al., 2015
caudal hematopoietic tissue hematopoietic multipotent progenitor cell decreased amount, abnormal	la2Tg + MO1-klf6a	standard conditions	Fig. 3 from Xue et al., 2017
blood island cell cycle process quality, abnormal	sd2Tg + MO1-klf6a	standard conditions	Fig. 6 from Xue et al., 2015
blood island cell population proliferation decreased process quality, abnormal	sd2Tg + MO1-klf6a	standard conditions	Fig. 6 from Xue et al., 2015
caudal vein plexus blood vessel endothelial cell migration decreased process quality, abnormal	ci5Tg; y7Tg + MO1-klf6a	standard conditions	Fig 4 from Wen et al., 2021
caudal hematopoietic tissue hematopoietic stem cell decreased amount, abnormal	ioz1Tg; s896Tg + MO1-klf6a	standard conditions	Fig. 3 from Xue et al., 2017
caudal hematopoietic tissue hematopoietic multipotent progenitor cell decreased amount, abnormal	la2Tg; s896Tg + MO1-klf6a	standard conditions	Fig. 3 from Xue et al., 2017
caudal vein plexus cell-cell junction maintenance decreased process quality, abnormal	cdh5^cqu2Tg; cqu6Tg + MO1-klf6a	standard conditions	Fig 5 from Wen et al., 2021
caudal vein plexus actin cytoskeleton organization decreased process quality, abnormal	cdh5^cqu2Tg; cqu6Tg + MO1-klf6a	standard conditions	Fig 5 from Wen et al., 2021
caudal vein plexus blood vessel remodeling decreased process quality, abnormal	cdh5^cqu2Tg; cqu6Tg + MO1-klf6a	standard conditions	Fig 5 from Wen et al., 2021

Citations