ZFIN Morpholino: MO1-rarab

Target Location

Genome Build: GRCz11Chromosome: 3

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-rarab

No data available

Phenotype

Phenotype resulting from MO1-rarab

Phenotype	Fish	Figures
liver decreased size, abnormal	WT + MO1-rarab	Fig. 3 from Garnaas et al., 2012
pectoral fin absent, abnormal	AB/TU + MO1-rarab	Fig. 4 from He et al., 2011
pectoral fin aplastic, abnormal	WT + MO1-rarab	Fig. 5 from Linville et al., 2009
pectoral fin bud aplastic, abnormal	WT + MO1-rarab	Fig. 5 from Linville et al., 2009
pectoral fin fold endochondral bone absent, abnormal	AB/TU + MO1-rarab	Fig. 4 from He et al., 2011

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Phenotype of all Fish created by or utilizing MO1-rarab

Phenotype	Fish	Conditions	Figures
pectoral fin absent, abnormal	AB/TU + MO1-rarab	standard conditions	Fig. 4 from He et al., 2011
pectoral fin fold endochondral bone absent, abnormal	AB/TU + MO1-rarab	standard conditions	Fig. 4 from He et al., 2011
pectoral fin fold scapulocoracoid absent, abnormal	AB/TU + MO1-rarab	standard conditions	Fig. 4 from He et al., 2011
pectoral fin bud aplastic, abnormal	WT + MO1-rarab	standard conditions	Fig. 5 from Linville et al., 2009
liver decreased size, abnormal	WT + MO1-rarab	standard conditions	Fig. 3 from Garnaas et al., 2012

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Citations

Include unpublished citations

Samarut, E., Gaudin, C., Hughes, S., Gillet, B., de Bernard, S., Jouve, P.E., Buffat, L., Allot, A., Lecompte, O., Berekelya, L., Rochette-Egly, C., and Laudet, V. (2014) Retinoic acid receptor subtype-specific transcriptotypes in the early zebrafish embryo. Molecular endocrinology (Baltimore, Md.). 28(2):260-272
D'Aniello, E., Rydeen, A.B., Anderson, J.L., Mandal, A., and Waxman, J.S. (2013) Depletion of Retinoic Acid Receptors Initiates a Novel Positive Feedback Mechanism that Promotes Teratogenic Increases in Retinoic Acid. PLoS Genetics. 9(8):e1003689
Garnaas, M.K., Cutting, C.C., Meyers, A., Kelsey, P.B., Harris, J.M., North, T.E., and Goessling, W. (2012) Rargb regulates organ laterality in a zebrafish model of right atrial isomerism. Developmental Biology. 372(2):178-189
He, X., Yan, Y.L., Eberhart, J.K., Herpin, A., Wagner, T.U., Schartl, M., and Postlethwait, J.H. (2011) miR-196 regulates axial patterning and pectoral appendage initiation. Developmental Biology. 357(2):463-77
Stevens, C.B., Cameron, D.A., and Stenkamp, D.L. (2011) Plasticity of photoreceptor-generating retinal progenitors revealed by prolonged retinoic acid exposure. BMC Developmental Biology. 11(1):51
Linville, A., Radtke, K., Waxman, J.S., Yelon, D., and Schilling, T.F. (2009) Combinatorial roles for zebrafish retinoic acid receptors in the hindbrain, limbs and pharyngeal arches. Developmental Biology. 325(1):60-70
Stafford, D., White, R.J., Kinkel, M.D., Linville, A., Schilling, T.F., and Prince, V.E. (2006) Retinoids signal directly to zebrafish endoderm to specify insulin-expressing {beta}-cells. Development (Cambridge, England). 133(5):949-956

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