ZFIN Morpholino: MO1-fn1b

Target Location

Genome Build: GRCz11Chromosome: 1

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-fn1b

No data available

Phenotype

Phenotype resulting from MO1-fn1b

No data available

Phenotype of all Fish created by or utilizing MO1-fn1b

Phenotype	Fish	Conditions	Figures
myotome myosin filament disorganized, abnormal	WT + MO1-fn1a + MO1-fn1b + MO2-fn1b	standard conditions	Fig. 2 , Fig. 3 , Fig. 4 from Snow et al., 2008
myotome muscle tendon junction morphology, abnormal	WT + MO1-fn1a + MO1-fn1b + MO2-fn1b	standard conditions	Fig. 2 from Snow et al., 2008
somite shape, abnormal	WT + MO1-fn1a + MO1-fn1b + MO2-fn1b	standard conditions	Fig. 1 from Snow et al., 2008
myotome actin filament increased length, abnormal	WT + MO1-fn1a + MO1-fn1b + MO2-fn1b	standard conditions	Fig. 2 , Fig. 3 from Snow et al., 2008
myotome variant shape, abnormal	WT + MO1-fn1a + MO1-fn1b + MO2-fn1b	standard conditions	Fig. 1 , Fig. 2 from Snow et al., 2008

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Citations

Include unpublished citations

Hipke, K., Pitter, B., Hruscha, A., van Bebber, F., Modic, M., Bansal, V., Lewandowski, S.A., Orozco, D., Edbauer, D., Bonn, S., Haass, C., Pohl, U., Montanez, E., Schmid, B. (2023) Loss of TDP-43 causes ectopic endothelial sprouting and migration defects through increased fibronectin, vcam 1 and integrin α4/β1. Frontiers in cell and developmental biology. 11:11699621169962
Prince, D.J., Jessen, J.R. (2019) Dorsal convergence of gastrula cells requires a Vangl2 and adhesion protein-dependent change in protrusive activity. Development (Cambridge, England). 146(22):
Rho, S.S., Kobayashi, I., Oguri-Nakamura, E., Ando, K., Fujiwara, M., Kamimura, N., Hirata, H., Iida, A., Iwai, Y., Mochizuki, N., Fukuhara, S. (2019) Rap1b Promotes Notch-Signal-Mediated Hematopoietic Stem Cell Development by Enhancing Integrin-Mediated Cell Adhesion. Developmental Cell. 49(5):681-696.e6
Love, A.M., Prince, D.J., Jessen, J.R. (2018) Vangl2-dependent regulation of membrane protrusions and directed migration requires a fibronectin extracellular matrix. Development (Cambridge, England). 145(22):
Cheng, P., Andersen, P., Hassel, D., Kaynak, B.L., Limphong, P., Juergensen, L., Kwon, C., and Srivastava, D. (2013) Fibronectin mediates mesendodermal cell fate decisions. Development (Cambridge, England). 140(12):2587-2596
Chiu, C.H., Chou, C.W., Takada, S., and Liu, Y.W. (2012) Development and fibronectin signaling requirements of the zebrafish interrenal vessel. PLoS One. 7(8):e43040
Latimer, A., and Jessen, J.R. (2010) Extracellular matrix assembly and organization during zebrafish gastrulation. Matrix biology : journal of the International Society for Matrix Biology. 29(2):89-96
Snow, C.J., Peterson, M.T., Khalil, A., and Henry, C.A. (2008) Muscle development is disrupted in zebrafish embryos deficient for fibronectin. Developmental Dynamics : an official publication of the American Association of Anatomists. 237(9):2542-2553
Jülich, D., Geisler, R., Tübingen 2000 Screen Consortium, and Holley, S.A. (2005) Integrinalpha5 and Delta/Notch Signaling Have Complementary Spatiotemporal Requirements during Zebrafish Somitogenesis. Developmental Cell. 8(4):575-586

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