ZFIN Morpholino: MO1-tdgf1

Target Location

Genome Build: GRCz11Chromosome: 10

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-tdgf1

No data available

Phenotype

Phenotype resulting from MO1-tdgf1

Phenotype	Fish	Figures
larval heart development decreased process quality, abnormal	WT + MO1-tdgf1	Fig. 3 from Deshwar et al., 2016
nodal signaling pathway decreased occurrence, abnormal	WT + MO1-tdgf1	Fig. 2 from Deshwar et al., 2016
tail bud increased size, abnormal	WT + MO1-tdgf1 + MO4-tp53	Fig. 3 from O'Neill et al., 2013
whole organism physical object quality, abnormal	WT + MO1-tdgf1 + MO4-tp53	Fig. S6 from Moreno-Ayala et al., 2015

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Phenotype of all Fish created by or utilizing MO1-tdgf1

Phenotype	Fish	Conditions	Figures
tail bud increased size, abnormal	WT + MO1-tdgf1	standard conditions	Fig. 3 from O'Neill et al., 2013
nodal signaling pathway decreased occurrence, abnormal	WT + MO1-tdgf1	standard conditions	Fig. 2 from Deshwar et al., 2016
larval heart development decreased process quality, abnormal	WT + MO1-tdgf1	standard conditions	Fig. 3 from Deshwar et al., 2016
whole organism physical object quality, abnormal	WT + MO1-tdgf1 + MO4-tp53	standard conditions	Fig. S6 from Moreno-Ayala et al., 2015
tail bud increased size, abnormal	WT + MO1-tdgf1 + MO4-tp53	standard conditions	Fig. 3 from O'Neill et al., 2013

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Citations

Include unpublished citations

Garland, M.A., Sengupta, S., Mathew, L.K., Truong, L., de Jong, E., Piersma, A.H., La Du, J., Tanguay, R.L. (2019) Glucocorticoid receptor-dependent induction of cripto-1 (one-eyed pinhead) inhibits zebrafish caudal fin regeneration. Toxicology reports. 6:529-537
Deshwar, A.R., Chng, S.C., Ho, L., Reversade, B., Scott, I.C. (2016) The Apelin receptor enhances Nodal/TGFβ signaling to ensure proper cardiac development. eLIFE. 5
Xue, Y., Xing, C., Zhang, W., Chen, C., Xu, J., Meng, A., Pan, Y. (2016) Coordinate involvement of Nodal-dependent inhibition and Wnt-dependent activation in the maintenance of organizer-specific bmp2b in zebrafish. The International journal of developmental biology. 60(1-2-3):13-19
Moreno-Ayala, R., Schnabel, D., Salas-Vidal, E., Lomelí, H. (2015) PIAS-like protein Zimp7 is required for the restriction of the Zebrafish organizer and mesoderm development. Developmental Biology. 403(1):89-100
O'Neill, K., and Thorpe, C. (2013) BMP signaling and spadetail regulate exit of muscle precursors from the zebrafish tailbud. Developmental Biology. 375(2):117-127
Chen, Y.Y., Harris, M.P., Levesque, M.P., Nüsslein-Volhard, C., and Sonawane, M. (2012) Heterogeneity across the dorso-ventral axis in zebrafish EVL is regulated by a novel module consisting of sox, snail1a and max genes. Mechanisms of Development. 129(1-4):13-23
Kwon, H.J., and Riley, B.B. (2009) Mesendodermal signals required for otic induction: Bmp-antagonists cooperate with Fgf and can facilitate formation of ectopic otic tissue. Developmental Dynamics : an official publication of the American Association of Anatomists. 238(6):1582-1594
Hall, C., Flores, M.V., Murison, G., Crosier, K., and Crosier, P. (2006) An essential role for zebrafish Fgfrl1 during gill cartilage development. Mechanisms of Development. 123(12):925-940
Feldman, B. and Stemple, D.L. (2001) Morpholino phenocopies of sqt, oep, and ntl mutations. Genesis (New York, N.Y. : 2000). 30(3):175-177
Phillips, B.T., Bolding, K., and Riley, B.B. (2001) Zebrafish fgf3 and fgf8 encode redundant functions required for otic placode induction. Developmental Biology. 235(2):351-365

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