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ZDB-IMAGE-241025-12

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Ventura Fernandes et al., 2024 - Standardizing CRISPR-Cas13 knockdown technique to investigate the role of cdh2 gene in pituitary development through growth hormone expression and transcription factors

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Figure 2

Gene expression graph (A)cdh2 at 24 hpf in WT and cdh2 knockdown larvae; (***p.<0,0001) (B)cdh2 temporal expression in WT larvae from 24 to 96 hpf; (C)cdh2 temporal expression in cdh2 knockdown larvae from 24 to 96 hpf; (D) Temporal expression of gh1 at 48, 72, and 96 hpf in WT larvae. (E) Temporal expression of gh1 at 48, 72, and 96 hpf in cdh2 knockdown larvae. (F) Expression of gh1 in cdh2 knockdown larvae compared to WT at 48 hpf (*p.<0.05). (G) Expression of gh1 in cdh2 knockdown larvae compared to WT 72 hpf (NS). (H)pit1 temporal expression in cdh2 knockdown larvae from 24 to 96 hpf. (I)pit1 expression at 48 hpf in cdh2 knockdown larvae compared to WT larvae (NS). (J)prop1 temporal expression in cdh2 knockdown larvae from 24 to 96 hpf. (K)prop1 expression at 48 hpf in cdh2 knockdown larvae compared to WT (NS).

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Endocrinol (Lausanne)