IMAGE

Figure 4

ID

ZDB-IMAGE-211216-19

Genes

ace
ace2

Publication

Kim et al., 2021 - The effect of renin-angiotensin-aldosterone system inhibitors on organ-specific ace2 expression in zebrafish and its implications for COVID-19

All Figures

Figures for Kim et al., 2021

Image

Figure Caption

Figure 4 Tissue-specific up-regulation of ace2 expression by RAAS inhibitors. The ace2 expression was significantly increased in captopril and olmesartan treated groups compared to the DMSO control in the gill, heart, and kidney (n = 6 per gene-organ-drug combination, *p < 0.05, **p < 0.01, ***p < 0.001 unpaired t test). Olmesartan also increased ace2 expression in the intestine (n = 6, p < 0.05, unpaired t test). Aliskiren treatment significantly decreased the ace2 expression in the heart; captopril treatment decreased ace expression in the heart, intestine, and the kidney (n = 6, p < 0.05, unpaired t test). Olm: olmesartan, Cap: captopril, Ali: aliskiren, Amlo: amlodipine.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Sci. Rep.