IMAGE

Fig. 7

ID

ZDB-IMAGE-161101-17

Genes

Antibodies

zn-5

Source

Figures for Choudhry et al., 2013

Image

Figure Caption

Fig. 7

tbx1 and wnt11r regulate Alcama levels, and alcama regulates heart looping and differentiation.

(A, C) ISH analysis on 48 hpf embryos showing that wnt11r^-/- mutants have unaffected tbx1 expression. (B, D, E, F) Antibody staining showing that wnt11r^-/- (D) and tbx1^-/- (F) mutants have down-regulated Alcama expression when compared to WT siblings (B, E). cmlc2 ISH on 48 hpf embryos showing the various looping phenotypes observed in alcama morphants (H) and proper looping in an uninjected larva (G). notch1b is expressed in the AVC endocardium in an uninjected larva at 48 hpf (I), but is down-regulated in alcama morphants (J). Scale bars: 50 µm.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

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