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Fig. 3
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Fig. 3
Expression of genes encoding RA pathway components is expanded dorsally in the CMZ of gdf6a mutants. Lateral views of whole-mount eyes from 32, 48 and 60hpf embryos showing expression (purple) of the genes indicated to the left of the rows. Genes shown encode enzymes required for RA synthesis (rdh10a and aldh1a3), a direct transcriptional target of the RA pathway (nr2f5), a cytosolic RA-buffering protein (crabp2a) and an enzyme responsible for RA catabolism (cyp26a1).
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