Fig. S1
- ID
- ZDB-IMAGE-150420-8
- Genes
- Publication
- Paolini et al., 2015 - Asymmetric inheritance of the apical domain and self-renewal of retinal ganglion cell progenitors depend on Anillin function
- All Figures
- Figures for Paolini et al., 2015
Fig. S1 Reciprocal regulation between Anillin and Ath5. (A) Ath5-/- (lakritz) mutant embryos retain anillin expression in the central retina where progenitors fail to exit the cell cycle and to differentiate into RGCs (highlighted by the cxcr4b expression in the wild-type retina). Scale bar: 21 µm. Anterior is always to the left, dorsal is to the top. (B) UCSC genome browser (https://genome.ucsc.edu/) overview of the anillin locus. Red-circled area shows the overlap between histone 3 lysine 4 monomethylation marks (indicative of cis-regulatory activity) at 24 hpf (blue) with Ath5 consensus binding site (black) 5 kb upstream of anillin transcription start site.