Gene
anln
- ID
- ZDB-GENE-030131-4486
- Name
- anillin, actin binding protein
- Symbol
- anln Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to have GTP-Rho binding activity. Involved in asymmetric cell division; glomerular filtration; and glomerulus development. Predicted to localize to actomyosin contractile ring. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 8. Is expressed in brain; optic cup; optic tectum; and retina. Orthologous to human ANLN (anillin actin binding protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| focal segmental glomerulosclerosis 8 | Alliance | Focal segmental glomerulosclerosis 8 | 616032 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR012966 | Anillin homology domain |
| Domain | IPR031970 | Anillin, N-terminal domain |
| Domain | IPR037840 | Anillin, PH domain |
| Family | IPR051364 | Cytokinesis and Rho signaling-related protein |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Anillin homology domain | Anillin, N-terminal domain | Anillin, PH domain | Cytokinesis and Rho signaling-related protein | PH-like domain superfamily | Pleckstrin homology domain |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A286Y917
|
1171 | ||||||
|
UniProtKB:F1QJH8
|
1153 |
Interactions and Pathways
No data available
Plasmids
No data available