Fig. 7 osr1 expression is independent of sox32 and acts to limit endodermal cell differentiation. A, B: Lateral views, dorsal on the right. A′, B′: Animal pole views, dorsal bottom. osr1 expression in the germ ring (A, A′) is unaffected in sox32 morphant embryos, which lack all endoderm derivatives. C–J: Animal pole views, dorsal bottom. foxa2 expression in control (C), osr1 knockdown (D), sox32 knockdown (E), and combined osr1, sox32 knockdown (F) reveals increased foxa2-expressing cells in osr1- and combined osr1-, sox32-deficient embryos. sox17 expression in control (G), osr1 knockdown (H), sox32 knockdown (I), and combined osr1, sox32 knockdown (J) reveals increased sox17-expressing cells in osr1- and combined osr1-, sox32-deficient embryos.
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