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Fig. 3
hmx4 morphants have defects in RA signaling. (A) otx2 is expanded in hmx4 morphants (extent of domain marked by the black line), while vhnf1 (B) and meis3 (C) are reduced in hmx4 morphants at 90% epiboly. (D) hoxd4a (blue) in 10s hmx4 morphants is reduced, while krox20 (red) expression in r3 and r5 is unchanged.
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Reprinted from Developmental Biology, 355(1), Gongal, P.A., March, L.D., Holly, V.L., Pillay, L.M., Berry-Wynne, K.M., Kagechika, H., and Waskiewicz, A.J., Hmx4 regulates Sonic hedgehog signaling through control of retinoic acid synthesis during forebrain patterning, 55-64, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.