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Fig. 3
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Fig. 3
Loss of pes function reduces oligodendrocyte gene expression.
Transverse sections through spinal cords of 4 dpf wild-type (A–C) and pesvu166 -/- (D–F) larvae processed for in situ RNA hybridization. Arrowheads indicate oligodendrocytes. Reaction products are greatly reduced in mutant relative to wild type. (G) Average number of labeled cells in the dorsal and ventral spinal cord. Ten sections from ten larvae of each genotype were counted. Asterisk (*) indicates pj0.05 by Student′s T-test. (H) Relative expression levels of the CNS myelin genes mpz and 36k measured by quantitative PCR.
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