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Fig. S13
Blockage of FGF Pathway Affected the Translocation of YY1 during Zebrafish Development.
GFP-tagged zebrafish YY1 mRNA (200 pg) was injected into one-cell stage embryos, and treated with DMSO (A-D), Hedgehog pathway inhibitor Cyclopamine (E-H), Notch pathway inhibitor DAPT (I-L), RA pathway inhibitor DEAB (M-P), or FGF pathway inhibitor SU5402 (Q-T) as described previously. Confocal microscopy was performed at 24 hpf using an anti-GFP antibody. Hoechst staining was also performed to mark the nucleus. All embryos were lateral views with anterior to the left.
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Reprinted from Cell, 139(3), Yue, R., Kang, J., Zhao, C., Hu, W., Tang, Y., Liu, X., and Pei, G., Beta-arrestin1 regulates zebrafish hematopoiesis through binding to YY1 and relieving polycomb group repression, 535-546, Copyright (2009) with permission from Elsevier. Full text @ Cell